Protein Information

Name CFTR
Synonyms ABC35; ABCC 7; ABCC7; ATP binding cassette transporter sub family C member 7; CF; CFTR; CFTR/MRP; MRP 7…

Compound Information

Name paraquat
CAS 1,1′-dimethyl-4,4′-bipyridinium

Reference List

PubMed Abstract RScore(About this table)
15206577 Satomi Y, Tsuchiya W, Mihara K, Ota M, Kasahara Y, Akahori F: Gene expression analysis of the lung following paraquat administration in rats using DNA microarray. J Toxicol Sci. 2004 May;29(2):91-100.

These differentially expressed genes following paraquat treatment were classified as follows: 5 neurotransmitter receptor genes; 4 transporter genes; 4 voltage-gated ion channel genes; 2 lipid metabolism enzyme genes; 2 G-proteins involved in endocytosis and exocytosis genes; 7 cytokine genes; 4 ADP ribosylation genes involved in cell death and regeneration; CFTR gene, which is the causal gene for cystic fibrosis; neurofibromatosis type 1 gene, which is the causal gene for the neurofibromatosis type 1 that is known to accompany pulmonary fibrosis; and the causal gene for spinocerebellar ataxia.
31(0,1,1,1) Details