| Name | Hsp70 |
|---|---|
| Synonyms | APG 2; APG2; HS24/P52; HSP70RY; HSPA 4; HSPA4; Heat shock 70 kDa protein 4; Heat shock 70 related protein APG 2… |
| Name | paraquat |
|---|---|
| CAS | 1,1′-dimethyl-4,4′-bipyridinium |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16216701 | Donaire V, Niso M, Moran JM, Garcia L, Gonzalez-Polo RA, Soler G, Fuentes JM: Heat shock proteins protect both MPP (+) and paraquat neurotoxicity. Brain Res Bull. 2005 Nov 30;67(6):509-14. Epub 2005 Sep 2. Heat shock pre-treatment prior to the addition of MPP (+) and paraquat significantly reduced cell death and led to an increase in the synthesis of Hsp 27 and Hsp70 proteins. |
81(1,1,1,1) | Details |
| 11472763 | Minois N: Resistance to stress as a function of age in transgenic Drosophila melanogaster overexpressing Hsp70. J Insect Physiol. 2001 Sep;47(9):1007-1012. The resistances to starvation, paraquat, and cold in flies from 1 to 7 week-old have been measured. |
3(0,0,0,3) | Details |
| 12653483 | Wirth D, Christians E, Munaut C, Dessy C, Foidart JM, Gustin P: Differential heat shock gene hsp70-1 response to toxicants revealed by in vivo study of lungs in transgenic mice. Cell Stress Chaperones. 2002 Oct;7(4):387-95. Members of heat shock proteins (Hsp70) family have been considered to respond to a large variety of stressful conditions. We found that hsp70-1 promoter was stimulated by heat shock and cadmium but not by ozone, paraquat, and parathion, even if these chemicals induced respiratory distress and lung inflammation. |
2(0,0,0,2) | Details |
| 16184763 | Batulan Z, Nalbantoglu J, Durham HD: Nonsteroidal anti-inflammatory drugs differentially affect the heat shock response in cultured spinal cord cells. Cell Stress Chaperones. 2005 Autumn;10(3):185-96. Because overexpression of the inducible heat shock protein 70 (Hsp70) was neuroprotective in a culture model of motor neuron disease, this study investigated whether NSAIDs induce Hsp70 and confer cytoprotection in motor neurons of dissociated spinal cord cultures exposed to various stresses. At concentrations that increased Hsp70 in heat shocked glial cells, failed to delay death of motor neurons exposed to hyperthermia, paraquat-mediated oxidative stress, and excitotoxicity. |
1(0,0,0,1) | Details |