Protein Information

Name carbonic anhydrase
Synonyms CA IX; CA1; Carbonic anhydrase I; CA2; CAII; Carbonic anhydrase II; Carbonic dehydratase; Carbonic anhydrase III…

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
1849715 Pogell BM, Rowland SS, Steinmann KE, Speedie MK, Hoskin FC: Genetic and biochemical evidence for the lack of significant hydrolysis of soman by a Flavobacterium parathion hydrolase. Appl Environ Microbiol. 1991 Feb;57(2):610-1.

Pure recombinant Flavobacterium parathion hydrolase (an organophosphorus acid anhydrase) from Streptomyces lividans was found to hydrolyze the toxic nerve agent soman at only 0.1% of the rate observed with parathion as substrate.
31(0,1,1,1) Details
15271511 Echizen T, Ibrahim MM, Nakata K, Izumi M, Ichikawa K, Shiro M: Nucleophilic reaction by carbonic anhydrase model zinc compound: characterization of intermediates for CO2 hydration and phosphoester hydrolysis. J Inorg Biochem. 2004 Aug;98(8):1347-60.

The carbonic anhydrase model compound [L1Zn (OH (2))](2+) was applied for the hydrolysis of phosphoesters, parathion and bis (p-nitrophenyl) phosphate (BNPP (-)).
8(0,0,1,3) Details
7704828 Rani NL, Lalithakumari D: Degradation of methyl parathion by Pseudomonas putida. Can J Microbiol. 1994 Dec;40(12):1000-6.

The bacterium elaborated the enzyme organophosphorus acid anhydrase, which hydrolyzed methyl parathion to p-nitrophenol. p-Nitrophenol was further degraded to hydroquinone and 1,2,4-benzenetriol.
31(0,1,1,1) Details
1450576 Martinez-Tabche L, Estrada B, Galar I: Parathion and salinity effects on gills and mesonephros carbonic anhydrase activity of the fish Oreochromis hornorum. Bull Environ Contam Toxicol. 1992 Dec;49(6):929-34.
6(0,0,1,1) Details
15019311 Santos HR, Cintra WM, Aracava Y, Maciel CM, Castro NG, Albuquerque EX: Spine density and dendritic branching pattern of hippocampal CA1 pyramidal neurons in neonatal rats chronically exposed to the organophosphate paraoxon. Neurotoxicology. 2004 Mar;25(3):481-94.

The organophosphate cholinesterase (ChE) inhibitor paraoxon is the oxidized active metabolite of parathion, a pesticide whose use in agriculture has been matter of increasing concern.
2(0,0,0,2) Details
630118 Rao AN, Brown AK, Rieder RF, Clegg JB, Marsh WL: Aplastic anemia with fetallike erythropoiesis following androgen therapy. Blood. 1978 Apr;51(4):711-9.


During these responses the subject's erythrocytes exhibited an increased i antigen score and a low level of red cell carbonic anhydrase.
1(0,0,0,1) Details