Protein Information

Name glutamine synthetase
Synonyms GLNS; GLUL; GS; Glutamate ammonia ligase; Glutamate ammonia ligase; Glutamine synthase; Glutamine synthetase; PIG43…

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
1981826 Reddy MS, Jayaprada P, Rao KV: Impact of methylparathion and malathion on cholinergic and non-cholinergic enzyme systems of penaeid prawn, Metapenaeus monoceros. Biochem Int. 1990 Nov;22(4):769-79.


The nervous tissue AChE, BUChE and glutaminase activity levels were significantly inhibited, whereas glutamine synthetase activity, acetylcholine and glutamine contents were increased significantly following the sublethal exposure of prawn, Metapenaeus, monoceros to methylparathion and malathion.
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15541749 Zurich MG, Honegger P, Schilter B, Costa LG, Monnet-Tschudi F: Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos. Toxicol Appl Pharmacol. 2004 Dec 1;201(2):97-104.

In contrast, trichloropyridinol induced a much stronger decrease in glutamine synthetase activity, the enzymatic marker of astrocytes.
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