Name | Lipoxygenase (protein family or complex) |
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Synonyms | arachidonate lipoxygenase; arachidonate lipoxygenases; lipoxygenase; lipoxygenases |
Name | copper sulfate |
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CAS | sulfuric acid copper(2+) salt (1:1) |
PubMed | Abstract | RScore(About this table) | |
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9261142 | Oorni K, Pentikainen MO, Annila A, Kovanen PT: Oxidation of low density lipoprotein particles decreases their ability to bind to human aortic proteoglycans. J Biol Chem. 1997 Aug 22;272(34):21303-11. We therefore treated LDL with various substances: copper sulfate, 2,2'-azobis (2-amidinopropane) hydrochloride (AAPH), soybean lipoxygenase, and mouse peritoneal macrophages, and determined the extent to which the oxidatively modified LDL bound to human aortic proteoglycans in an affinity column. |
32(0,1,1,2) | Details |
11352990 | Chang MY, Potter-Perigo S, Wight TN, Chait A: Oxidized LDL bind to nonproteoglycan components of smooth muscle extracellular matrices. J Lipid Res. 2001 May;42(5):824-33. LDL was modified with 2,2-azo-bis (2-amidinopropane)-2HCl, soybean lipoxygenase, and phospholipase or copper sulfate. |
31(0,1,1,1) | Details |
1546066 | Derian CK, Lewis DF: Activation of 15-lipoxygenase by low density lipoprotein in vascular endothelial cells. Prostaglandins Leukot Essent Fatty Acids. 1992 Jan;45(1):49-57. |
7(0,0,0,7) | Details |
11590223 | Edelstein C, Nakajima K, Pfaffinger D, Scanu AM: Oxidative events cause degradation of apoB-100 but not of apo [a] and facilitate enzymatic cleavage of both proteins. J Lipid Res. 2001 Oct;42(10):1664-70. In this study, we examined the in vitro susceptibility of LDL and Lp [a], obtained from the same donor, to oxidation by either Cu (2)+ or the combined Crotalus adamanteus phospholipase A2 and soybean lipoxygenase system, monitoring the course of the reaction by the generation of conjugated dienes and fatty acids. |
1(0,0,0,1) | Details |
8400082 | Keane WF, O'Donnell MP, Kasiske BL, Kim Y: Oxidative modification of low-density lipoproteins by mesangial cells. J Am Soc Nephrol. 1993 Aug;4(2):187-94. Native LDL subjected to chemical oxidation by copper sulfate also inhibited mesangial cell proliferation. |
0(0,0,0,0) | Details |