Name | dopamine transporter |
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Synonyms | DA transporter; DAT1; DAT; DAT 1; Dopamine transporter; SLC6A3; Sodium dependent dopamine transporter; Dopamine transporters… |
Name | permethrin |
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CAS | (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate |
PubMed | Abstract | RScore(About this table) | |
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14555407 | Pittman JT, Dodd CA, Klein BG: Immunohistochemical changes in the mouse striatum induced by the pyrethroid insecticide permethrin. Int J Toxicol. 2003 Sep-Oct;22(5):359-70. These data suggest that a low dose of permethrin can reduce the amount of dopamine transporter immunoreactive protein in the caudate-putamen. |
34(0,1,1,4) | Details |
12428726 | Bloomquist JR, Barlow RL, Gillette JS, Li W, Kirby ML: Selective effects of insecticides on nigrostriatal dopaminergic nerve pathways. Neurotoxicology. 2002 Oct;23(4-5):537-44. Western blot analysis confirmed increased levels of dopamine transporter (DAT) protein in the striatum of mice treated with heptachlor and permethrin. |
6(0,0,1,1) | Details |
16005927 | Elwan MA, Richardson JR, Guillot TS, Caudle WM, Miller GW: Pyrethroid pesticide-induced alterations in dopamine transporter function. . Toxicol Appl Pharmacol. 2006 Mar 15;211(3):188-97. Epub 2005 Jul 11. Here, we report that repeated exposure (3 injections over 2 weeks) of mice to two commonly used pyrethroid pesticides, deltamethrin (3 mg/kg) and permethrin (0.8 mg/kg), increases DAT-mediated uptake by 31 and 28%, respectively. |
2(0,0,0,2) | Details |
17597311 | Kou J, Bloomquist JR: Neurotoxicity in murine striatal dopaminergic pathways following long-term application of low doses of permethrin and MPTP. Toxicol Lett. 2007 Jul 10;171(3):154-61. Epub 2007 May 21. Alterations in the expression of tyrosine hydroxylase (TH), dopamine transporter (DAT), and alpha-synuclein proteins were analyzed 1 day after the last PM treatment using western blot assay. |
1(0,0,0,1) | Details |
14575646 | Gillette JS, Bloomquist JR: Differential up-regulation of striatal dopamine transporter and alpha-synuclein by the pyrethroid insecticide permethrin. Toxicol Appl Pharmacol. 2003 Nov 1;192(3):287-93. |
7(0,0,1,2) | Details |