Protein Information

Name estrogen receptor
Synonyms ER; ERA; ER alpha; ERalpha; ESR; ESR 1; ESR1; ESRA…

Compound Information

Name phoxim
CAS 4-ethoxy-7-phenyl-3,5-dioxa-6-aza-4-phosphaoct-6-ene-8-nitrile 4-sulfide

Reference List

PubMed Abstract RScore(About this table)
12396874 Chen H, Xiao J, Hu G, Zhou J, Xiao H, Wang X: Estrogenicity of organophosphorus and pyrethroid pesticides. J Toxicol Environ Health A. 2002 Oct 11;65(19):1419-35.

The present study was undertaken to evaluate the estrogenic activities of nine pesticides (phoxim, malathion, monocrotophos, dimethoate, opunal, fenvalerate, cypermethrin, permethrin, and deltamethrin) using three in vitro methods [E-Screen assay, estrogen receptor (ER) competitive binding assay, and pS2 expression assay].
31(0,1,1,1) Details
15799245 Chen R, Li A, Zhu T, Li C, Liu Q, Chang HC, Zhou J: JWA--a novel environmental-responsive gene, involved in estrogen receptor-associated signal pathway in MCF-7 and MDA-MB-231 breast carcinoma cells. J Toxicol Environ Health A. 2005 Mar 26;68(6):445-56.

The pyrethroid insecticide fenvalerate and the organophosphorus insecticide phoxim are now the most widely used agents for indoor pest control in China.
2(0,0,0,2) Details