phoxim

Identification (Source:EPA,EU)

ID 234
Name phoxim
CAS 14816-18-3
IUPAC
Inchi InChI=1S/C12H15N2O3PS/c1-3-15-18(19,16-4-2)17-14-12(10-13)11-8-6-5-7-9-11/h5-9H,3-4H2,1-2H3
CIPAC 364
EPA Code 598800
Formula C12H15N2O3PS
SMILES N#C/C(=N\OP(=S)(OCC)OCC)c1ccccc1
Status Not Approved

Classification

Mode of Action Non-systemic with contact and stomach action. Short activity period. Acetylcholinesterase (AChE) inhibitor.
Pesticide Type Insecticide, Disinfectant
Chemical Group Organophosphate
Classification oxime organothiophosphate insecticides
aliphatic organothiophosphate insecticides
organothiophosphate acaricides
organothiophosphate insecticides

Properties (Source:PubChem)

Molecular Weight 298.3
Physical State Yellow liquid
AlogP 3.05
H-Bond Donor 0
H-Bond Acceptor 6
Surface Area 293.32
Polar Surface Area 105.74

Structure



ChemMapper Search Option (Docunmentation of ChemMapper)

3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Aquatic invertebrates Acute 48 hour EC50 0.00081 mg l-1
Fish Acute 96 hour LC50 0.22 mg l-1
Mammals Acute oral LD50 > 2000 mg kg-1
Mammals Short term dietary NOEL 15 ppm diet

Related targets

Target Name RScore (About this table)
Acetylcholinesterase 1032(11,15,16,27) Details
somatotropins 81(1,1,1,1) Details
glutathione S transferases 62(0,2,2,2) Details
estrogen receptor 33(0,1,1,3) Details
acid phosphatase 32(0,1,1,2) Details
CMAP 31(0,1,1,1) Details
neuropathy target esterase 31(0,1,1,1) Details
catalase 31(0,1,1,1) Details
cytochrome P450 monooxygenases 31(0,1,1,1) Details
beta adrenoceptor (protein family or complex) 31(0,1,1,1) Details
superoxide dismutase 31(0,1,1,1) Details
alkaline phosphatase 31(0,1,1,1) Details
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