Name | lysyl oxidase |
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Synonyms | LOX; Lysyl oxidase; Protein lysine 6 oxidase; Protein lysine 6 oxidase precursor; Lysyl oxidases; Protein lysine 6 oxidases; Protein lysine 6 oxidase precursors |
Name | butylamine |
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CAS | 2-butanamine |
PubMed | Abstract | RScore(About this table) | |
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2885317 | Williamson PR, Kagan HM: Alpha-mechanism of action of lysyl oxidase. J Biol Chem. 1987 Jun 15;262(17):8196-201. Tetranitromethane (TNM) was employed as an electrophilic reagent to probe for the lysyl oxidase-catalyzed processing of n-butylamine to an intermediate carbanion during the oxidation of this amine to according to a prior description of the use of TNM to trap enzyme-generated carbanion intermediates (Christen, P. and Riordan, J. |
abstraction and carbanion formation in the 150(1,3,4,5) | Details |
1977746 | Gacheru SN, Trackman PC, Shah MA, O'Gara CY, Spacciapoli P, Greenaway FT, Kagan HM: Structural and catalytic properties of lysyl oxidase. . J Biol Chem. 1990 Nov 5;265(31):19022-7. A difference absorption band also developed at 300-310 nm upon anaerobic incubation of pyrroloquinoline the putative carbonyl cofactor of lysyl oxidase, with n-butylamine. |
in 36(0,1,1,6) | Details |
10556569 | Akagawa M, Wako Y, Suyama K: Lysyl oxidase coupled with catalase in egg shell membrane. Biochim Biophys Acta. 1999 Sep 14;1434(1):151-60. The activity was determined by measuring the enzymatic conversion of n-butylamine and to and Nalpha-acetyl-L- respectively. |
7(0,0,0,7) | Details |
2873143 | Williamson PR, Kagan HM: Reaction pathway of bovine aortic lysyl oxidase. . J Biol Chem. 1986 Jul 15;261(20):9477-82. Lineweaver-Burk plots revealed a pattern of parallel lines when the oxidation of n-butylamine was followed at different fixed concentrations of consistent with a "ping-pong" kinetic mechanism in which the is produced and released before the binding of the second substrate. |
4(0,0,0,4) | Details |
11178979 | Akagawa M, Suyama K: Characterization of a model compound for the cofactor of lysyl oxidase. Biochem Biophys Res Commun. 2001 Feb 16;281(1):193-9. The model compound, 4-butylamino-5-methyl-o- was prepared from n-butylamine and by the oxidation with and characterized by spectroscopic analyses. |
tyrosylquinone 3(0,0,0,3) | Details |
12785842 | Mure M, Wang SX, Klinman JP: Synthesis and characterization of model compounds of the tyrosyl cofactor of lysyl oxidase. J Am Chem Soc. 2003 May 21;125(20):6113-25. Characterization of a 1,6-adduct between an o- and butylamine (3-n-butylamino-5-ethyl-1,2- 13) confirms the assignment of LTQ as a 1,4-addition product. |
1(0,0,0,1) | Details |