Protein Information

Name elastin
Synonyms ELN; WS; WBS; Elastin; Elastin precursor; SVAS; Tropoelastin; Elastins…

Compound Information

Name butylamine
CAS 2-butanamine

Reference List

PubMed Abstract RScore(About this table)
2901988 Tur SS, Lerch K: Unprecedented lysyloxidase activity of Pichia pastoris benzylamine oxidase. FEBS Lett. 1988 Sep 26;238(1):74-6.

It has a broad substrate specificity ranging from butylamine to peptidyl lysine in collagen and elastin.
31(0,1,1,1) Details
10992159 Akagawa M, Suyama K: Mechanism of formation of elastin crosslinks. Connect Tissue Res. 2000;41(2):131-41.

We examined the formation of quaternary pyridinium crosslinks of elastin formed by condensation of lysine and allysine residues using the model compounds propanal (allysine) and n-butylamine (lysine) under quasi-physiological conditions.
7(0,0,1,2) Details
10562423 Akagawa M, Yamazaki K, Suyama K: Cyclopentenosine, major trifunctional crosslinking amino acid isolated from acid hydrolysate of elastin. Arch Biochem Biophys. 1999 Dec 1;372(1):112-20.

A model reaction for the formation of the CP crosslink using model compounds for allysine (propanal) and lysine (n-butylamine) demonstrated that CP is composed of 2-cyclopenten-1-one and alpha, beta, gamma, delta-unsaturated aldehyde derived from three allysine residues.
2(0,0,0,2) Details