Protein Information

Name methemoglobin
Synonyms Abnormal hemoglobin; G gamma globin; Gamma 2 globin; HBG 2; HBG2; Hb F Ggamma; Hemoglobin gamma G; Hemoglobin gamma 2 chain…

Compound Information

Name propanil
CAS

Reference List

PubMed Abstract RScore(About this table)
1162701 Chow AY, Murphy SD: Propanil (3,4-dichloropropionanilide)-induced methemoglobin formation in relation to its metabolism in vitro. Toxicol Appl Pharmacol. 1975 Jul;33(1):14-20.
31(0,1,1,1) Details
2237922 McMillan DC, McRae TA, Hinson JA: Propanil-induced methemoglobinemia and hemoglobin binding in the rat. Toxicol Appl Pharmacol. 1990 Sep 15;105(3):503-7.

Administration of [ring-U-14C] propanil (3,4-dichloropropionanilide) to male Sprague-Dawley rats (30, 100, and 300 mg/kg, ip) increased the formation of methemoglobin at the two highest doses.
19(0,0,3,4) Details
4714336 Singleton SD, Murphy SD: Propanil (3,4-dichloropropionanilide)-induced methemoglobin formation in mice in relation to acylamidase activity. Toxicol Appl Pharmacol. 1973 May;25(1):20-9.
6(0,0,1,1) Details
12507053 Eddleston M, Rajapakshe M, Roberts D, Reginald K, Rezvi Sheriff MH, Dissanayake W, Buckley N: Severe propanil [N-(3,4-dichlorophenyl) propanamide] pesticide self-poisoning. J Toxicol Clin Toxicol. 2002;40(7):847-54.

Management was difficult given the lack of i.v. methylene blue, inability to measure methemoglobin levels, and paucity of intensive care unit beds.
1(0,0,0,1) Details