| Name | glutathione S transferase |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | propiconazole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10336094 | Egaas E, Sandvik M, Fjeld E, Kallqvist T, Goksoyr A, Svensen A: Some effects of the fungicide propiconazole on cytochrome P450 and glutathione S-transferase in brown trout (Salmo trutta). Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1999 Mar;122(3):337-44. The fungicide propiconazole (1-(2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-ylmethyl) -1H-1,2,4-triazole) induced the hepatic cytochrome P4501A (CYP1A) activity towards ethoxyresorufin-O-deethylase (EROD), the content of CYP1A protein as quantified by enzyme-linked immunosorbent assay (ELISA) and the glutathione S-transferase (GST) activity towards the three commonly used substrates CDNB (1-chloro-2,4-dinitrobenzene), cumene hydroperoxide (CU) and ethachrynic acid (EA) in brown trout (Salmo trutta) depending on dose and body weight. |
37(0,1,2,2) | Details |
| 12408568 | Almli B, Egaas E, Christiansen A, Eklo OM, Lode O, Kallqvist T: Effects of three fungicides alone and in combination on glutathione S-transferase activity (GST) and cytochrome P-450 (CYP 1A1) in the liver and gill of brown trout (Salmo trutta). Mar Environ Res. 2002 Sep-Dec;54(3-5):237-40. In order to evaluate the gill glutathione S-transferase (GST) activity as a biomarker of effect of fungicide exposure in juvenile brown trout (Salmo trutta), the fungicides propiconazole [(R,S)-1-[2-(2,4-diclophenyl)-4-propyl-1,3-dioolan-2-ylmetyl]-1H-1,2,4-tri azole] and [(+/-)-cis-4-[3-(4-tert-butylphenyl)-2-metyl propyl]-2,6 dimetylmorfolinc] were administrated in the water separately and together in a static system (80 microg/l for each pesticide) for 5 days. |
7(0,0,1,2) | Details |
| 17350344 | Johansen NS, Moen LH, Egaas E: Sterol demethylation inhibitor fungicides as disruptors of insect development and inducers of glutathione S-transferase activities in Mamestra brassicae. Comp Biochem Physiol C Toxicol Pharmacol. 2007 Apr;145(3):473-83. Epub 2007 Feb 12. To study physiological and biochemical effects of demethylation inhibitor (DMI) fungicides on non-target insects, larvae of the cabbage moth, Mamestra brassicae L., were exposed orally to propiconazole, (R,S)-1-[2-(2,4-diclophenyl)-4-propyl-1,3-dioolan-2-ylmetyl]-1H-1,2,4-tria zole (100, 200 and 600 mg L (-1)) and (+/-)-cis-4-[3-(4-tert-butylphenyl)-2-methylpropyl] 2,6-dimethylmorpholinc (10, 100, 200 and 600 mg L (-1)) in a semi-synthetic diet. |
2(0,0,0,2) | Details |
| 1862543 | Cabral R, Hoshiya T, Hakoi K, Hasegawa R, Fukushima S, Ito N: A rapid in vivo bioassay for the carcinogenicity of pesticides. Tumori. 1991 Jun 30;77(3):185-8. Hepatocarcinogenic potential was assessed by comparing the number and area of glutathione s-transferase (placental form) -positive foci in the liver with those of controls given diethylnitrosamine alone. Positive results were seen with Chinomethionat, Phosmet and Propiconazole; the results obtained with Captan and Prochloraz were borderline; Benomyl, Daminozide and Folpet gave negative results. |
1(0,0,0,1) | Details |
| 3190755 | Leslie C, Reidy GF, Stacey NH: The effects of propiconazole on hepatic xenobiotic biotransformation in the rat. Biochem Pharmacol. 1988 Nov 1;37(21):4177-81. p-hydroxylase and cytosolic glutathione S-transferase activities were unchanged. |
1(0,0,0,1) | Details |