Protein Information

Name BIN2
Synonyms BIN 2; BIN2; BRAP 1; BRAP1; Breast cancer associated protein 1; Bridging integrator 2; Breast cancer associated protein 1s; Bridging integrator 2s

Compound Information

Name benomyl
CAS

Reference List

PubMed Abstract RScore(About this table)
7916460 Chen X, Sullivan DS, Huffaker TC: Two yeast genes with similarity to TCP-1 are required for microtubule and actin function in vivo. Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):9111-5.

Mutations in BIN2 and BIN3 cause defects in microtubule and actin assembly in vivo and confer supersensitivity to the microtubule-destabilizing drug benomyl.
8(0,0,1,3) Details
7916461 Vinh DB, Drubin DG: A yeast TCP-1-like protein is required for actin function in vivo. Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):9116-20.

We show that anc2-1 mutants contain abnormal and disorganized actin structures, are defective in cellular morphogenesis, and are hypersensitive to the microtubule inhibitor benomyl.
Mutations in BIN2 and BIN3, two other genes that encode TCP-1-like proteins, also enhance the phenotypes of actin mutants.
1(0,0,0,1) Details