benomyl
Identification (Source:EPA,EU)
ID |
130 |
Name |
benomyl |
CAS |
17804-35-2 |
IUPAC |
methyl 1-(butylcarbamoyl)benzimidazol-2-ylcarbamate |
Inchi |
IInChI=1S/C14H18N4O3/c1-3-4-9-15-13(19)18-11-8-6-5-7-10(11)16-12(18)17-14(20)21-2/h5-8H,3-4,9H2,1-2H3,(H,15,19)(H,16,17,20) |
CIPAC |
206 |
EPA Code |
099101 |
Formula |
C14H18N4O3 |
SMILES |
O=C(n1c2ccccc2nc1NC(=O)OC)NCCCC |
Status |
Not Approved |
Classification
Properties (Source:PubChem)
Molecular Weight |
290.32 |
Physical State |
Tan coloured crystals |
AlogP |
2.965 |
H-Bond Donor |
2 |
H-Bond Acceptor |
4 |
Surface Area |
291.34 |
Polar Surface Area |
85.25 |
Structure
Ecotoxicology (Source:PPDB,IPM)
Species |
Method |
Study Time |
Dose Type |
Value |
Algae |
Acute |
72 hour |
EC50, growth |
2 mg l-1 |
Aquatic crustaceans |
Acute |
96 hour |
LC50 |
0.14 mg l-1 |
Aquatic invertebrates |
Chronic |
21 day |
NOEC |
0.025 mg l-1 |
Aquatic invertebrates |
Acute |
48 hour |
EC50 |
0.28 mg l-1 |
Aquatic plants |
Acute |
7 day |
EC50, biomass |
2.2 mg l-1 |
Birds |
Acute |
|
LD50 |
1000 mg kg-1 |
Earthworms |
Acute |
14 day |
LD50 |
10.5 mg kg-1 |
Fish |
Acute |
96 hour |
LC50 |
0.17 mg l-1 |
Fish |
Chronic |
21 day |
NOEC |
0.011 mg l-1 |
Honeybees |
Acute |
48 hour |
LD50 |
10 μg bee-1 |
Mammals |
Acute oral |
|
LD50 |
> 10000 mg kg-1 |
Mammals |
Short term dietary |
|
NOEL |
2500 ppm diet |
Mammals |
Short term dietary |
|
NOEL |
125 mg kg-1 |
|
Bio-concentration factor |
|
CT50 |
Not available days |
|
Bio-concentration factor |
|
BCF |
27 |
Related targets
Target Name |
RScore (About this table) |
|
FLR1
|
593(5,10,14,23) |
Details |
alpha tubulin
|
320(2,5,8,55) |
Details |
ALDH2
|
187(1,4,4,17) |
Details |
Aldehyde dehydrogenases (protein family or complex)
|
153(1,3,3,13) |
Details |
cytochrome P450 (protein family or complex)
|
113(1,2,2,3) |
Details |
dynein (protein family or complex)
|
125(1,1,3,35) |
Details |
XRN1
|
86(1,1,1,6) |
Details |
chitinase
|
83(1,1,1,3) |
Details |
CENP B
|
81(1,1,1,1) |
Details |
aldo keto reductase (protein family or complex)
|
81(1,1,1,1) |
Details |
Cdc20p
|
66(0,2,2,6) |
Details |
kinesin
|
59(0,1,1,29) |
Details |
CDR1
|
53(0,1,2,18) |
Details |
PP2A
|
39(0,1,1,9) |
Details |
YAP1
|
34(0,1,1,4) |
Details |
activin A
|
33(0,1,1,3) |
Details |
protein kinase A (protein family or complex)
|
33(0,1,1,3) |
Details |
VIK1
|
32(0,1,1,2) |
Details |
neural cell adhesion molecule
|
32(0,1,1,2) |
Details |
protein a
|
32(0,1,1,2) |
Details |
histone deacetylase (protein family or complex)
|
32(0,1,1,2) |
Details |
cytochrome P450 monooxygenase
|
31(0,1,1,1) |
Details |
dihydrofolate reductase
|
31(0,1,1,1) |
Details |
CDC20
|
31(0,1,1,1) |
Details |
NCAM
|
31(0,1,1,1) |
Details |
MDR1
|
48(0,0,3,33) |
Details |
gamma tubulin (protein family or complex)
|
29(0,0,0,29) |
Details |
casein
|
18(0,0,3,3) |
Details |
SAC3
|
14(0,0,1,9) |
Details |
brains
|
12(0,0,2,2) |
Details |
budding uninhibited by benomyl
|
12(0,0,0,12) |
Details |
alcohol dehydrogenases (protein family or complex)
|
12(0,0,1,7) |
Details |
C18
|
11(0,0,1,6) |
Details |
G beta
|
11(0,0,1,6) |
Details |
CDR2
|
11(0,0,1,6) |
Details |
MAD2
|
10(0,0,1,5) |
Details |
histone H4
|
10(0,0,1,5) |
Details |
BIN3
|
9(0,0,1,4) |
Details |
BIN2
|
9(0,0,1,4) |
Details |
Myosin
|
9(0,0,1,4) |
Details |
arylsulfatase
|
9(0,0,1,4) |
Details |
Ajuba
|
9(0,0,0,9) |
Details |
glutamyl transpeptidase
|
8(0,0,1,3) |
Details |
LYS2
|
8(0,0,1,3) |
Details |
Ran binding protein 1
|
7(0,0,0,7) |
Details |
CSM1
|
7(0,0,1,2) |
Details |
CDC5
|
7(0,0,1,2) |
Details |
Mediator complex (protein family or complex)
|
7(0,0,1,2) |
Details |
CARB
|
7(0,0,1,2) |
Details |
microtubule associated protein
|
7(0,0,0,7) |
Details |
PLC1
|
7(0,0,1,2) |
Details |
coronin (protein family or complex)
|
7(0,0,0,7) |
Details |
cyclin B1
|
6(0,0,1,1) |
Details |
C40
|
6(0,0,1,1) |
Details |
TFIIS
|
6(0,0,0,6) |
Details |
ha 1
|
6(0,0,1,1) |
Details |
dynactin (protein family or complex)
|
6(0,0,0,6) |
Details |
RMI1
|
6(0,0,1,1) |
Details |
AP4
|
6(0,0,1,1) |
Details |
protein is
|
6(0,0,0,6) |
Details |
ubiquitin
|
6(0,0,0,6) |
Details |
MMS
|
6(0,0,1,1) |
Details |
cyclin B2
|
6(0,0,1,1) |
Details |
PAT1
|
6(0,0,0,6) |
Details |
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