| Name | YAP1 |
|---|---|
| Synonyms | 65 kDa Yes associated protein; YAP; YAP 1; YAP 2; YAP1; YAP2; YAP65; Yes associated protein… |
| Name | benomyl |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11162502 | Tenreiro S, Fernandes AR, Sa-Correia I: Transcriptional activation of FLR1 gene during Saccharomyces cerevisiae adaptation to growth with benomyl: role of Yap1p and Pdr3p. Biochem Biophys Res Commun. 2001 Jan 12;280(1):216-22. YAP1 gene was proved to be a determinant of benomyl resistance; the duration of the adaptation period preceding cell division under benomyl stress was longer for the Deltayap1 population, presumably due to the abolishment of FLR1 activation during latency. |
32(0,1,1,2) | Details |
| 15980350 | Harry JB, Oliver BG, Song JL, Silver PM, Little JT, Choiniere J, White TC: Drug-induced regulation of the MDR1 promoter in Candida albicans. Antimicrob Agents Chemother. 2005 Jul;49(7):2785-92. MDR1 mRNA levels in a susceptible clinical isolate are induced by benomyl (BEN) but not by other drugs previously shown to induce MDR1. The T-BHP induction region contains a sequence that resembles the YAP1-responsive element (YRE) in Saccharomyces cerevisiae. |
1(0,0,0,1) | Details |
| 17046176 | Chen KH, Miyazaki T, Tsai HF, Bennett JE: The bZip transcription factor Cgap1p is involved in multidrug resistance and required for activation of multidrug transporter gene CgFLR1 in Candida glabrata. Gene. 2007 Jan 15;386(1-2):63-72. Epub 2006 Aug 24. In this study, we characterized structural and functional properties of CgAP1, a Saccharomyces cerevisiae YAP1 ortholog, which encodes a transcription factor involved in various stress responses. Deletion of CgAP1 led to decreased resistance to peroxide, 4-nitroquinoline-N-oxide (4-NQO), benomyl, and cadmium which could be fully recovered by reintroduction of an intact CgAP1. |
1(0,0,0,1) | Details |