| Name | CDR2 |
|---|---|
| Synonyms | CDR 2; CDR2; CDR62; Cerebellar degeneration related antigen 2 (62kD); Cerebellar degeneration related autoantigen 62kd; Cerebellar degeneration related protein (62kD); Cerebellar degeneration related protein 2; Cerebellar degeneration related autoantigen 2… |
| Name | benomyl |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15273122 | Karababa M, Coste AT, Rognon B, Bille J, Sanglard D: Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters. Antimicrob Agents Chemother. 2004 Aug;48(8):3064-79. Upregulation of these genes can also be achieved by exposure to fluphenazine, resulting in specific upregulation of CDR1 and CDR2 and by exposure to benomyl, resulting in specific CaMDR1 upregulation. |
9(0,0,1,4) | Details |
| 17159223 | Rognon B, Kozovska Z, Coste AT, Pardini G, Sanglard D: Identification of promoter elements responsible for the regulation of MDR1 from Candida albicans, a major facilitator transporter involved in azole resistance. Microbiology. 2006 Dec;152(Pt 12):3701-22. In an azole-susceptible strain, transcription of this reporter is transiently upregulated in response to either benomyl or H (2) O (2), whereas its expression is constitutively high in an azole-resistant strain (FR2). Two cis-acting regulatory elements within the MDR1 promoter were identified that are necessary and sufficient to confer the same transcriptional responses on a heterologous promoter (CDR2). |
1(0,0,0,1) | Details |
| 9532737 | Krishnamurthy S, Gupta V, Prasad R, Panwar SL, Prasad R: Expression of CDR1, a multidrug resistance gene of Candida albicans: transcriptional activation by heat shock, drugs and human steroid hormones. FEMS Microbiol Lett. 1998 Mar 15;160(2):191-7. Elevated levels of CDR1 and CDR2 (a homologue of CDR1) mRNA were found in some azole-resistant clinical isolates of C. albicans. CaMDR1 (benomyl-resistant) expression, however, did not differ among all the resistant isolates. |
1(0,0,0,1) | Details |