Protein Information

Name histone H4
Synonyms H4/A; H4FA; HIST1H4A; H4/I; H4FI; HIST1H4B; H4/g; H4FG…

Compound Information

Name benomyl
CAS

Reference List

PubMed Abstract RScore(About this table)
12917332 Le Masson I, Yu DY, Jensen K, Chevalier A, Courbeyrette R, Boulard Y, Smith MM, Mann C: Yaf9, a novel NuA4 histone acetyltransferase subunit, is required for the cellular response to spindle stress in yeast. Mol Cell Biol. 2003 Sep;23(17):6086-102.

Two other NuA4 mutants (esa1-1851 and yng2 Delta) and nonacetylatable histone H4 mutants were also sensitive to benomyl.
7(0,0,1,2) Details
19332560 Polevoda B, Hoskins J, Sherman F: Properties of Nat4, an N (alpha)-acetyltransferase of Saccharomyces cerevisiae that modifies N termini of histones H2A and H4. Mol Cell Biol. 2009 Jun;29(11):2913-24. Epub 2009 Mar 30.

The analysis of chimeric proteins with various N-terminal segments of histone H4 fused to iso-1-cytochrome c revealed that efficient acetylation by NatD required at least 30 to 50 amino acid residues of the N terminus of histone H4.
The nat4-Delta strain showed several minor phenotypes, including sensitivity to 3-aminotriazole, benomyl, and thiabendazole.
3(0,0,0,3) Details