11960377 |
Sarafan-Vasseur N, Lamy A, Bourguignon J, Le Pessot F, Hieter P, Sesboue R, Bastard C, Frebourg T, Flaman JM: Overexpression of B-type cyclins alters chromosomal segregation. Oncogene. 2002 Mar 27;21(13):2051-7.
Overexpression of cyclin B2 and cyclin B1, the two human homologs of Clb5, in the CIN indicator strain resulted also into a sectoring phenotype and induced, like overexpression of Clb5, an abnormal sensitivity to benomyl, indicating that overexpression of B-type cyclins alters the spindle checkpoint. |
6(0,0,1,1) |
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