Protein Information

Name histone deacetylase (protein family or complex)
Synonyms Histone deacetylase; Histone deacetylases

Compound Information

Name benomyl
CAS

Reference List

PubMed Abstract RScore(About this table)
12917332 Le Masson I, Yu DY, Jensen K, Chevalier A, Courbeyrette R, Boulard Y, Smith MM, Mann C: Yaf9, a novel NuA4 histone acetyltransferase subunit, is required for the cellular response to spindle stress in yeast. Mol Cell Biol. 2003 Sep;23(17):6086-102.

Furthermore, wild-type budding yeast were more resistant to benomyl when grown in the presence of trichostatin A, a histone deacetylase inhibitor.
31(0,1,1,1) Details
16729061 Ye P, Peyser BD, Pan X, Boeke JD, Spencer FA, Bader JS: Gene function prediction from congruent synthetic lethal interactions in yeast. Mol Syst Biol. 2005;1:2005.0026. Epub 2005 Nov 22.

We predicted benomyl sensitivity and nuclear migration defects using congruence; these phenotypes were uncorrelated with direct synthetic lethality.
Synthetic lethal interactions between MEN and all components of the Sin3/Rpd3 histone deacetylase revealed a novel function for Sin3/Rpd3 in promoting mitotic exit in parallel to MEN.
1(0,0,0,1) Details