| Name | anticholinesterase |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | carbofuran |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1305879 | Kokshareva NV: [The therapeutic efficacy of alloxime in experimental pesticide poisoning]. Eksp Klin Farmakol. 1992 Nov-Dec;55(6):51-3. The new cholinesterase reactivator alloxime, 10 mg/kg, shows a marked therapeutical benefits in acute intoxication rats with carbamine pesticides such as carbofuran, pirimor, elocron. |
7(0,0,1,2) | Details |
| 7990167 | Gupta RC: Carbofuran toxicity. J Toxicol Environ Health. 1994 Dec;43(4):383-418. Carbofuran, an anticholinesterase is commonly used as an insecticide, nematicide, and acaricide in agricultural practice throughout the world. |
7(0,0,1,2) | Details |
| 1130829 | Ludke JL, Hill EF, Dieter MP: Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors. Arch Environ Contam Toxicol. 1975;3(1):1-21. Individuals that died from dietary exposure to parathion-1 or carbofuran had brain ChE activities below 55 percent of normal; although individuals could survive with brain ChE activity lower than 50 percent. |
1(0,0,0,1) | Details |
| 16358164 | Satar S, Satar S, Sebe A, Yesilagac H: Carbofuran poisoning among farm workers. Mt Sinai J Med. 2005 Nov;72(6):389-92. Serum pseudocholinesterase level was low in only one patient. |
1(0,0,0,1) | Details |
| 11286337 | Bachmann TT, Leca B, Vilatte F, Marty JL, Fournier D, Schmid RD: Improved multianalyte detection of organophosphates and carbamates with disposable multielectrode biosensors using recombinant mutants of Drosophila acetylcholinesterase and artificial neural networks. Biosens Bioelectron. 2000 Jun;15(3-4):193-201. Multisensors I and II were both used for inhibition analysis of binary paraoxon and carbofuran mixtures in a concentration range 0-5 microg/l, followed by data analysis using feed-forward ANN. Engineered variants of Drosophila melanogaster acetylcholinesterase (AChE) were used as biological receptors of AChE-multisensors for the simultaneous detection and discrimination of binary mixtures of cholinesterase-inhibiting insecticides. |
1(0,0,0,1) | Details |
| 7217860 | Barnett JB, Spyker-Cranmer JM, Avery DL, Hoberman AM: Immunocompetence over the lifespan of mice exposed in utero to carbofuran or diazinon: I. J Environ Pathol Toxicol. 1980 Nov;4(5-6):53-63. Pregnant F2 dihybrid mice received either a vehicle-control or 1 of 2 doses of the anticholinesterase pesticides Carbofuran (0.01 or 0.50 mg/kg) or Diazinon (0.18 or 9.00 mg/kg) in the diet daily throughout gestation. |
6(0,0,1,1) | Details |
| 2778846 | Gupta RC, Kadel WL: Prevention and antagonism of acute carbofuran intoxication by memantine and atropine. J Toxicol Environ Health. 1989;28(1):111-22. Male Sprague-Dawley rats administered with a sublethal acute dose of carbofuran (1.5 mg/kg, sc) developed the observable toxic signs of anticholinesterase nature within 5-7 min. |
6(0,0,1,1) | Details |
| 15179037 | Kim SJ, Kim JE, Ko BH, Moon IS: Carbofuran induces apoptosis of rat cortical neurons and down-regulates surface alpha7 subunit of acetylcholine receptors. Mol Cells. 2004 Apr 30;17(2):242-7. Carbofuran (CF), an anticholinesterase is one of the most widely used N-methylcarbamate esters in insect and nematode control. |
6(0,0,1,1) | Details |
| 15362815 | Wobeser G, Bollinger T, Leighton FA, Blakley B, Mineau P: Secondary poisoning of eagles following intentional poisoning of coyotes with anticholinesterase pesticides in western Canada. J Wildl Dis. 2004 Apr;40(2):163-72. Carbofuran was identified in nine incidents. |
4(0,0,0,4) | Details |
| 8827674 | Elliott JE, Langelier KM, Mineau P, Wilson LK: Poisoning of bald eagles and red-tailed hawks by carbofuran and fensulfothion in the Fraser Delta of British Columbia, Canada. J Wildl Dis. 1996 Jul;32(3):486-91. During the winter of 1990 in the Fraser Delta of British Columbia, Canada, nine birds of prey were found with symptoms of anticholinesterase poisoning. |
1(0,0,0,1) | Details |
| 2322020 | Hussain M, Yoshida K, Atiemo M, Johnston D: Occupational exposure of grain farmers to carbofuran. . Arch Environ Contam Toxicol. 1990 Mar-Apr;19(2):197-204. Blood samples were analyzed for acetylcholinesterase (AChE), pseudocholinesterase (ChE) and several other blood parameters. |
1(0,0,0,1) | Details |
| 12860061 | Souza da Silva R, Cognato Gde P, Vuaden FC, Rezende MF, Thiesen FV, Fauth Mda G, Bogo MR, Bonan CD, Dias RD: Different sensitivity of Ca (2+)-ATPase and cholinesterase to pure and commercial pesticides in nervous ganglia of Phyllocaulis soleiformis (Mollusca). Comp Biochem Physiol C Toxicol Pharmacol. 2003 Jun;135(2):215-20. Both enzymes were insensitive to pure carbofuran (1 mM), (1 mM) and malathion (120 microM). |
4(0,0,0,4) | Details |
| 17504769 | McDaniel KL, Padilla S, Marshall RS, Phillips PM, Podhorniak L, Qian Y, Moser VC: Comparison of acute neurobehavioral and cholinesterase inhibitory effects of N-methylcarbamates in rat. Toxicol Sci. 2007 Aug;98(2):552-60. Epub 2007 May 15. The chemicals tested were carbaryl, carbofuran, formetanate, methiocarb, methomyl, oxamyl, and propoxur. |
3(0,0,0,3) | Details |
| 16518518 | Milatovic D, Gupta RC, Aschner M: Anticholinesterase toxicity and oxidative stress. ScientificWorldJournal. 2006 Feb 28;6:295-310. Pretreatment with (NMDA) receptor antagonist memantine, in combination with atropine sulfate, provides significant protection against inhibition of AChE, increases of ROS/RNS, and depletion of high-energy phosphates induced by DFP/carbofuran. |
3(0,0,0,3) | Details |
| 12408569 | Alves SR, Severino PC, Ibbotson DP, da Silva AZ, Lopes FR, Saenz LA, Bainy AC: Effects of furadan in the brown mussel Perna perna and in the mangrove oyster Crassostrea rhizophorae. Mar Environ Res. 2002 Sep-Dec;54(3-5):241-5. Glutathione S-transferase (GST), catalase (CAT) and cholinesterase (ChE) activities were measured in the gills of both species exposed to furadan (100 microg/l) for 96 h. |
1(0,0,0,1) | Details |
| 15253053 | Fleischli MA, Franson JC, Thomas NJ, Finley DL, Riley W Jr: Avian mortality events in the United States caused by anticholinesterase pesticides: a retrospective summary of National Wildlife Health Center records from 1980 to 2000. Arch Environ Contam Toxicol. 2004 May;46(4):542-50. Of 24 different pesticides identified, the most frequent were famphur (n = 59: 18%), carbofuran (n = 52; 15%), diazinon (n = 40; 12%), and fenthion (n = 17; 5.1%). |
3(0,0,0,3) | Details |
| 2810558 | Hill EF: Sex and storage affect cholinesterase activity in blood plasma of Japanese quail. J Wildl Dis. 1989 Oct;25(4):580-5. Effects of sex and storage of samples were studied as sources of variability by treating breeding Japanese quail (Coturnix japonica) with 3 mg of dicrotophos or carbofuran per kg of body weight and comparing blood plasma ChE activities for samples collected at 1 hr postdosage and assayed fresh, after 1 and 2 days of refrigeration (4 C), and after 1, 7 and 28 days of freezing (-25 C). |
2(0,0,0,2) | Details |
| 17726623 | Pathiratne A, Chandrasekera LW, De Seram PK: Effects of biological and technical factors on brain and muscle cholinesterases in Nile tilapia, Oreochromis niloticus: implications for biomonitoring contaminations. Arch Environ Contam Toxicol. 2008 Feb;54(2):309-17. Storage of tissues at -80 degrees C for 28 days had no significant effect on ChE activities in the control fish and the fish exposed to carbofuran. |
2(0,0,0,2) | Details |
| 1545210 | Ferslew KE, Hagardorn AN, McCormick WF: Poisoning from oral ingestion of carbofuran (Furadan 4F), a cholinesterase-inhibiting insecticide, and its effects on cholinesterase activity in various biological fluids. J Forensic Sci. 1992 Jan;37(1):337-44. |
195(2,3,3,5) | Details |
| 17364237 | Ahmed M, Rocha JB, Mazzanti CM, Morsch AL, Cargnelutti D, Correa M, Loro V, Morsch VM, Schetinger MR: Malathion, carbofuran and paraquat inhibit Bungarus sindanus (krait) venom acetylcholinesterase and human serum butyrylcholinesterase in vitro. Ecotoxicology. 2007 May;16(4):363-9. Epub 2007 Mar 16. |
89(1,1,2,4) | Details |
| 6853013 | Drevenkar V, Stengl B, Tkalcevic B, Vasilic Z: Occupational exposure control by simultaneous determination of N-methylcarbamates and organophosphorus pesticide residues in human urine. Int J Environ Anal Chem. 1983;14(3):215-30. Transesterification conversion efficiencies of N-methylcarbamates dioxacarb, carbofuran and OMS-22, calculated from the amount of the on-column produced O-methyl-N-methylcarbamate (DMC), were 96, 77 and 76% with detection limits of 8, 10 and 10 ng, respectively. The level of extracted N-methylcarbamates and the concentration of degradation products of organophosphorus pesticides detected in the urine of the same persons were correlated with the blood and plasma cholinesterase activities. |
2(0,0,0,2) | Details |
| 12942229 | Ivanov A, Evtugyn G, Budnikov H, Ricci F, Moscone D, Palleschi G: Cholinesterase sensors based on screen-printed electrodes for detection of organophosphorus and carbamic pesticides. Anal Bioanal Chem. 2003 Oct;377(4):624-31. Epub 2003 Aug 26. The biosensors developed make it possible to detect down to 2 x 10 (-8) mol L (-1) chloropyrifos-methyl, 5 x 10 (-8) mol L (-1) coumaphos, and 8 x 10 (-9) mol L (-1) carbofuran in aqueous solution and grape juice. |
2(0,0,0,2) | Details |
| 17423767 | Frank R, Braun HE, Wilkie I, Ewing R: A review of insecticide poisonings among domestic livestock in southern Ontario, Canada, 1982-1989. Can Vet J. 1991 Apr;32(4):219-226. Signs typical of cholinesterase inhibition caused by organophosphorus poisoning were observed in most cases. From 1982 to 1989, inclusive, 20 poisonings were investigated by the Ontario Ministry of Agriculture and Food following ingestion by domestic livestock of granular insecticides including terbufos (13 poisonings), disulfoton (two poisonings), fonofos (two poisonings), phorate (two poisonings), and carbofuran (one poisoning); all are used for rootworm (Diabrotica spp.) control in corn. |
2(0,0,0,2) | Details |
| 18699799 | Zeljezic D, Vrdoljak AL, Kopjar N, Radic B, Milkovic Kraus S: Cholinesterase-Inhibiting and Genotoxic Effects of Acute Carbofuran Intoxication in Man: A Case Report. Basic Clin Pharmacol Toxicol. 2008 Aug 11. |
89(1,1,2,4) | Details |
| 18937214 | Li H, Ricordel I, Tong L, Schopfer LM, Baud F, Megarbane B, Maury E, Masson P, Lockridge O: Carbofuran poisoning detected by mass spectrometry of butyrylcholinesterase adduct in human serum. J Appl Toxicol. 2009 Mar;29(2):149-55. Butyrylcholinesterase (BChE) in plasma is inhibited by carbofuran and serves as a biomarker of poisoning by carbofuran. |
88(1,1,2,3) | Details |
| 19269215 | Tennakoon S, Perera B, Haturusinghe L: Intentional poisoning cases of animals with anticholinesterase pesticide-carbofuran in Sri Lanka. Leg Med. 2009 Apr;11 Suppl 1:S500-2. Epub 2009 Mar 6. Carbofuran is a broad spectrum insecticide and nematicide which inhibits acetyl cholinesterase. |
87(1,1,2,2) | Details |
| 6510327 | Hill EF, Camardese MB: Toxicity of anticholinesterase insecticides to birds: technical grade versus granular formulations. Ecotoxicol Environ Saf. 1984 Dec;8(6):551-63. The test chemicals were Amaze 15G (isofenphos), Counter 15G (terbufos), Dasanit 15G (fensulfothion), Diazinon 14G (diazinon), Di-Syston 15G (disulfoton), Dyfonate 20G (fonofos), Furadan 10G (carbofuran), Lorsban 15G (chlorpyrifos), Nemacur 15G (fenamiphos), Parathion 10G (parathion), Tattoo 10G (bendiocarb), Temik 15G (aldicarb), and Thimet 15G (phorate). |
2(0,0,0,2) | Details |
| 603347 | Abdel-Aal YA: Multiple cholinesterases in rat brain homogenate. Arch Exp Veterinarmed. 1977;31(4):465-70. These two kinetic forms have different affinity to acetylthiocholine (34 fold), and different sensitivity to carbofuran, 2,2-dimethyl 2,3-dihadro-7-benzofuranyl methylcarbamate (33 fold). |
2(0,0,0,2) | Details |
| 656640 | Dieter MP, Ludke JL: Studies on combined effects of organophosphates or carbamates and morsodren in birds. Bull Environ Contam Toxicol. 1978 Apr;19(4):389-95. The degree of interaction between mercury and cholinesterase inhibiting pesticides was determined by comparing enzyme responses to sublethal dosages of parathion or carbofuran in quail fed 0.05, 0.5, or 5.0 ppm morsodren for 18 weeks. |
89(1,1,2,4) | Details |
| 2731661 | Casale GP, Bavari S, Connolly JJ: Inhibition of human serum complement activity by diisopropylfluorophosphate and selected anticholinesterase insecticides. Fundam Appl Toxicol. 1989 Apr;12(3):460-8. Since the widely used anticholinesterase insecticides inhibit serine esterases, the present study evaluated potencies of carbaryl, carbofuran, dichlorvos, and paraoxon to inhibit C' activities of a panel of normal human sera. |
83(1,1,1,3) | Details |
| 16704049 | Scholz NL, Truelove NK, Labenia JS, Baldwin DH, Collier TK: Dose-additive inhibition of chinook salmon acetylcholinesterase activity by mixtures of organophosphate and insecticides. Environ Toxicol Chem. 2006 May;25(5):1200-7. Anticholinesterase insecticides commonly co-occur in the environment. We extracted AChE from the olfactory nervous system of chinook salmon (Oncorhynchus tshawytscha) and investigated the inhibitory effects of organophosphates (the oxon derivatives of diazinon, chlorpyrifos, and malathion) and carbamates (carbaryl and carbofuran), alone and in two-way combinations. |
2(0,0,0,2) | Details |
| 7966439 | Gupta RC, Goad JT, Kadel WL: Cholinergic and noncholinergic changes in skeletal muscles by carbofuran and methyl parathion. J Toxicol Environ Health. 1994 Nov;43(3):291-304. The objective of this investigation was to determine the distribution of cholinergic (acetyl-cholinesterase, AChE) and noncholinergic markers in slow-, fast-, and mixed-fiber containing muscles (soleus, SOL; extensor digitorum longus, EDL; and diaphragm, DIA, respectively). |
2(0,0,0,2) | Details |
| 8343977 | Loewenstein Y, Denarie M, Zakut H, Soreq H: Molecular dissection of cholinesterase domains responsible for toxicity. Chem Biol Interact. 1993 Jun;87(1-3):209-16. Comparative inhibition profiles were derived for five N-methyl carbamates, mostly carbofuran derivatives, differing in length and branching of their hydrocarbonic chain towards human erythrocyte acetylcholinesterase (H.AChE), human serum butyrylcholinesterase (H.BChE) in its normal form or in a mutant form containing the point mutation Asp70--> Gly, and Drosophila nervous system ChE. |
83(1,1,1,3) | Details |
| 15719990 | Osten JR, Soares AM, Guilhermino L: Black-bellied whistling duck (Dendrocygna autumnalis) brain cholinesterase characterization and diagnosis of anticholinesterase pesticide exposure in wild populations from Mexico. Environ Toxicol Chem. 2005 Feb;24(2):313-7. Cholinesterase inhibition after exposure to pesticide mixtures predominantly was due to carbofuran. |
83(1,1,1,3) | Details |
| 9478101 | Lata S, Janiszewski J, Madej T: Accidental oral poisoning with in a 26-year-old patient. Przegl Lek. 1997;54(10):753-5. Acute, accidental, oral poisoning with carbofuran in a chronic alcoholic was presented. A role of an interview and physical symptoms in diagnosing the poisoning with cholinesterase inhibitors, a specific treatment conduct and its side effects were discussed. |
2(0,0,0,2) | Details |
| 17197007 | Padilla S, Marshall RS, Hunter DL, Lowit A: Time course of cholinesterase inhibition in adult rats treated acutely with carbaryl, carbofuran, formetanate, methomyl, methiocarb, oxamyl or propoxur. Toxicol Appl Pharmacol. 2007 Mar;219(2-3):202-9. Epub 2006 Nov 15. |
82(1,1,1,2) | Details |
| 1757408 | France JE, King JW: Supercritical fluid extraction/enzyme assay: a novel technique to screen for pesticide residues in meat products. J Assoc Off Anal Chem. 1991 Nov-Dec;74(6):1013-6. SFE of carbofuran-fortified frankfurters was coupled with an enzyme assay based on cholinesterase inhibition. |
81(1,1,1,1) | Details |
| 8349949 | Casale GP, Vennerstrom JL, Bavari S, Wang TL: Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected and organophosphate insecticides and congeners of carbaryl. Immunopharmacol Immunotoxicol. 1993 Mar-Jun;15(2-3):199-215. The anticholinesterase (antiCHE) insecticides, a large family of pesticides used extensively throughout the world, inhibit serine hydrolases by carbamylating or phosphorylating a serine residue at the catalytic site. The order of potency for T cell inhibition was carbaryl = dichlorvos > methiocarb > carbofuran > paraoxon > mevinphos > aldicarb = monocrotophos. |
1(0,0,0,1) | Details |
| 1527362 | Mostafa IY, Zayed SM, Farghaly M, Mahdy F: Bioavailability to rats and toxicity in mice of carbofuran residues bound to faba beans. J Environ Sci Health B. 1992 Aug;27(4):399-405. Feeding mice with bound carbofuran residues for 90 days led to inhibition of erythrocyte cholinesterase activity after 30 days (35-40%) while the plasma enzyme remained unaffected. |
81(1,1,1,1) | Details |
| 17254622 | Brasel JM, Collier AC, Pritsos CA: Differential toxic effects of Carbofuran and Diazinon on time of flight in pigeons (Columba livia): potential for pesticide effects on migration. Toxicol Appl Pharmacol. 2007 Mar;219(2-3):241-6. Epub 2006 Dec 6. Carbofuran, a and diazinon, an organophosphate, are among the most commonly implicated cholinesterase inhibitors in episodes of accidental avian toxicity and mortality. |
33(0,1,1,3) | Details |
| 3434890 | Poirier T, Farnos JM, Charpy E, Meyer G, Martignon M: [Acute poisoning by the anticholinesterase Ann Fr Anesth Reanim. 1987;6(5):457-9. A case is reported of voluntary acute carbofuran poisoning. |
1(0,0,0,1) | Details |
| 14730122 | Rizos E, Liberopoulos E, Kosta P, Efremidis S, Elisaf M: Carbofuran-induced acute pancreatitis. . JOP. 2004 Jan;5(1):44-7. Pseudocholinesterase levels returned to normal 7 days later and the patient was discharged in good physical condition one month after admission. |
1(0,0,0,1) | Details |
| 2035247 | Iyaniwura TT: Relative inhibition of rat plasma and erythrocyte cholinesterases by pesticide combinations. Vet Hum Toxicol. 1991 Apr;33(2):166-8. A selected combination of pesticides (carbofuran, oxamyl and propoxur were examined for cholinesterase (ChE) inhibition. |
32(0,1,1,2) | Details |
| 9528704 | Ibrahim H, Kheir R, Helmi S, Lewis J, Crane M: Effects of organophosphorus, pyrethroid and organochlorine pesticides, and a heavy metal on survival and cholinesterase activity of Chironomus riparius Meigen. Bull Environ Contam Toxicol. 1998 Mar;60(3):448-55. |
1(0,0,0,1) | Details |
| 2709439 | Gupta RC, Kadel WL: Concerted role of carboxylesterases in the potentiation of carbofuran toxicity by iso-OMPA pretreatment. J Toxicol Environ Health. 1989;26(4):447-57. The maximal CarbE inactivation in plasma (less than 14% remaining activity) following either drug indicated a tremendous nonspecific binding to non-AChE serine-containing enzymes. iso-OMPA pretreatment markedly potentiated carbofuran's anticholinesterase activity both in neuronal and in nonneuronal tissues. |
1(0,0,0,1) | Details |
| 16128077 | Zhang LJ, Min SG, Li GX, Xiong YM, Sun Y: [The mechanism of carbofuran interacts with calf thymus DNA] . Guang Pu Xue Yu Guang Pu Fen Xi. 2005 May;25(5):739-42. Acute and chronic occupational exposure of humans to carbofuran has been observed to cause cholinesterase inhibition, but little is known about the interaction of carbofuran with DNA. |
31(0,1,1,1) | Details |
| 6693000 | Ferguson PW, Dey MS, Jewell SA, Krieger RI: Carbofuran metabolism and toxicity in the rat. Fundam Appl Toxicol. 1984 Feb;4(1):14-21. Carbofuran absorption (peak plasma levels less than 7 min), distribution, and elimination (t1/2 = 29 +/- 5 min) occurred rapidly. 3-Hydroxycarbofuran, a significant oxidative metabolite of carbofuran with anticholinesterase activity, was rapidly formed and subject to enterohepatic circulation (plasma t1/2 = 64 +/- 5 min). |
31(0,1,1,1) | Details |
| 11833793 | Wilson LK, Elliott JE, Vernon RS, Smith BD, Szeto SY: Persistence and retention of active ingredients in four granular cholinesterase-inhibiting insecticides in agricultural soils of the lower Fraser River valley, British Columbia, Canada, with implications for wildlife poisoning. Environ Toxicol Chem. 2002 Feb;21(2):260-8. The persistence and retention of active ingredients in granules of Thimet 15G (phorate 15% by weight), Dyfonate 10G (fonofos 10% by weight), Counter 15G (terbufos 15% by weight), and Furadan 10G (carbofuran 10% by weight) were determined in silt loam and organic muck agricultural soils typical of the lower Fraser River valley (BC, Canada). |
1(0,0,0,1) | Details |
| 10073919 | : Farm worker illness following exposure to carbofuran and other pesticides--Fresno County California, 1998. MMWR Morb Mortal Wkly Rep. 1999 Feb 19;48(6):113-6. The findings indicated that the workers became ill after early reentry into a cotton field that had been sprayed with a cholinesterase-inhibiting pesticides |
1(0,0,0,1) | Details |
| 9523504 | Baban NK, Nunley DL, Borges AS Jr, Roy TM: Human sequelae of severe poisoning. Tenn Med. 1998 Mar;91(3):103-6. Carbofuran is a that functions as a cholinesterase inhibitor. |
31(0,1,1,1) | Details |
| 10696923 | Yang PY, Tsao TC, Lin JL, Lyu RK, Chiang PC: Carbofuran-induced delayed neuropathy. J Toxicol Clin Toxicol. 2000;38(1):43-6. We report what appears to be delayed neuropathy caused by poisoning with carbofuran, a cholinesterase-inhibiting although the certainty of diagnosis is somewhat limited by the lack of a sural nerve biopsy and spinal fluid examination. |
31(0,1,1,1) | Details |
| 666362 | Serat WF: Estimating a worker entry interval for the pesticide furadan 4F insecticide. Arch Environ Contam Toxicol. 1978;7(1):1-11. As pesticides share with these materials a common site for inhibition, the kinetic method was applied in estimating an entry interval for the carbofuran, applied to citrus and grapes as Furadan 4F. Thus, a measure of safety was built into the calculations which can then be used to establish safe reentry intervals to insure residue levels below the physiological threshold for cholinesterase inhibition. |
1(0,0,0,1) | Details |
| 739215 | Cranmer JS, Avery DL, Grady RR, Kitay JI: Postnatal endocrine dysfunction resulting from prenatal exposure to carbofuran, diazinon or chlordane. J Environ Pathol Toxicol. 1978 Nov-Dec;2(2):357-69. Exposure to lower doses of the anticholinesterase compounds, Diazinon or Carbofuran, resulted in impairment of hepatic metabolism of in vitro due to a loss in reductive capacity per unit liver weight. |
31(0,1,1,1) | Details |
| 8583636 | Hunt KA, Hooper MJ, Littrell EE: Carbofuran poisoning in herons: diagnosis using cholinesterase reactivation techniques. J Wildl Dis. 1995 Apr;31(2):186-92. |
12(0,0,2,2) | Details |
| 11993279 | Pogacnik L, Franko M: Validation of different commercially available cholinesterases for pesticide toxicity test. Ann Chim. 2002 Jan-Feb;92(1-2):93-101. A systematic study of different commercially available cholinesterases (AChEs from electric eel, human erythrocytes, bovine erythrocytes and BuChE from horse serum) for the FIA determination of some frequently used organophosphate (paraoxon, oxydemeton-methyl, triazophos, diazionon) and (carbofuran, propoxur) pesticides was carried out. |
10(0,0,1,5) | Details |
| 12485777 | Ciucu AA, Negulescu C, Baldwin RP: Detection of pesticides using an amperometric biosensor based on ferophthalocyanine chemically modified carbon paste electrode and immobilized bienzymatic system. Biosens Bioelectron. 2003 Mar;18(2-3):303-10. The activity of cholinesterase is non-competitively inhibited in the presence of pesticides. With this approach, up to 10 (-10) M of paraoxon and carbofuran can be detected. |
1(0,0,0,1) | Details |
| 8627921 | Augspurger T, Smith MR, Meteyer CU, Converse KA: Mortality of passerines adjacent to a North Carolina corn field treated with granular carbofuran. J Wildl Dis. 1996 Jan;32(1):113-6. Activity of brain cholinesterase (ChE) was inhibited by 14 to 48% in three of five specimens, and returned to normal levels after incubation. |
1(0,0,0,1) | Details |
| 18968286 | Pogacnik L, Franko M: Optimisation of FIA system for detection of organophosphorus and pesticides based on cholinesterase inhibition. Talanta. 2001 May 30;54(4):631-41. Responses to some frequently used organophosphorus (paraoxon, oxydemeton-methyl, triazophos) and (carbofuran, propoxur) pesticides were found to be dependent on the origin of cholinesterases. |
9(0,0,1,4) | Details |
| 10217931 | Huang J, Zhang S, Ding M, Zhou A, Zhang J, Zhang J: Acute effects of carbofuran in workers of two pesticide plants. Med Lav. 1998;89 Suppl 2:S105-11. During the investigation, 25 cases of acute carbofuran poisoning were diagnosed by their clinical picture and depressed cholinesterase activity in blood. |
8(0,0,1,3) | Details |
| 15261450 | Jarrard HE, Delaney KR, Kennedy CJ: Impacts of pesticides on olfactory neurophysiology and cholinesterase activity in coho salmon (Oncorhynchus kisutch). Aquat Toxicol. 2004 Aug 10;69(2):133-48. A neurophysiological measure of olfactory function, the electro-olfactogram (EOG), was used in this study to examine the impacts of acute localized exposure to three carbamates (the insecticide carbofuran, the antisapstain IPBC, and the fungicide mancozeb) on olfactory function in the coho salmon (Oncorhynchus kisutch). |
1(0,0,0,1) | Details |
| 18775593 | Laguerre C, Sanchez-Hernandez JC, Kohler HR, Triebskorn R, Capowiez Y, Rault M, Mazzia C: B-type esterases in the snail Xeropicta derbentina: an enzymological analysis to evaluate their use as biomarkers of pesticide exposure. Environ Pollut. 2009 Jan;157(1):199-207. Epub 2008 Sep 4. Specific cholinesterase and carboxylesterase activities were mainly obtained with acetylthiocholine (K (m)=77.2 mM; V (max)=38.2 mU/mg protein) and 1-naphthyl (K (m)=222 mM, V (max)=1095 mU/mg protein) substrates, respectively. Acetylcholinesterase activity was concentration-dependently inhibited by chlorpyrifos-oxon, dichlorvos, carbaryl and carbofuran (IC50=1.35x10 (-5)-3.80x10 (-8) M). |
1(0,0,0,1) | Details |
| 16442830 | Pinakini KS, Kumar TS: Serial cholinesterase estimation in poisoning. J Clin Forensic Med. 2006 Jul;13(5):274-6. Epub 2006 Jan 27. A fatal case of carbofuran poisoning is presented where serial cholinesterase estimation played a major role in the diagnosis of the same. |
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| 10918524 | Gupta RC, Goad JT, Milatovic D, Dettbarn WD: Cholinergic and noncholinergic brain biomarkers of insecticide exposure and effects. Hum Exp Toxicol. 2000 May;19(5):297-308. The objective of this investigation was to determine the distribution of cholinergic and noncholinergic biomarkers in discrete brain regions (cortex, stem, striatum, hippocampus, and cerebellum) of rats treated with (DMSO, controls), and insecticides such as carbofuran (CARB, 1.5 mg/kg, sc), or methyl parathion (MPTH, 5 mg/kg, ip). Both insecticides produced characteristic signs of anticholinesterase nature within 5-7 min after injection. |
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| 14709383 | Kok FN, Hasirci V: Determination of binary pesticide mixtures by an acetylcholinesterase- oxidase biosensor. Biosens Bioelectron. 2004 Feb 15;19(7):661-5. Enzyme immobilized membrane was used in the detection of anti-cholinesterase activity of aldicarb (AS), carbofuran (CF) and carbaryl (CL), as well as two mixtures, (AS+CF) and (AS+CL). |
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| 7128789 | Kokshareva NV: [Therapeutic effectiveness of diethyxime in poisoning by anticholinesterase-action pesticides]. Farmakol Toksikol. 1982 Jul-Aug;45(4):61-4. Unlike dipyroxime (10 mg/kg), a new cholinesterase reactivator diethyxime (20 mg/kg) exerts a therapeutic action in acute poisoning of rats with carbamine pesticides (carbofuran, elocron, pirimor, croneton). |
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| 15620756 | Rendon-von Osten J, Ortiz-Arana A, Guilhermino L, Soares AM: In vivo evaluation of three biomarkers in the mosquitofish (Gambusia yucatana) exposed to pesticides. Chemosphere. 2005 Feb;58(5):627-36. In this study, the acute toxicity and the in vivo effects of commercial chlorpyrifos, carbofuran and formulations on cholinesterase (ChE), glutathione S-transferase (GST) and lactate dehydrogenase (LDH) activities of the mosquitofish (Gambusia yucatana) were investigated. |
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