| Name | estrogen receptor alpha |
|---|---|
| Synonyms | ER; ERA; ER alpha; ERalpha; ESR; ESR 1; ESR1; ESRA… |
| Name | methiocarb |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19206145 | Han J, Park M, Kim JH, Kim A, Won M, Lee DR, Ko JJ, Yoon H, Sim SH, Lee K, Bae J: Increased expression of the testicular estrogen receptor alpha in adult mice exposed to low doses of methiocarb. J Appl Toxicol. 2009 Jul;29(5):446-51. Therefore, these results demonstrate, that although the exposure to methiocarb at low doses alters testicular ERalpha expression in adult mice, both sperm production and quality remain unaffected. |
43(0,1,3,3) | Details |
| 15130599 | Hofmeister MV, Bonefeld-Jorgensen EC: Effects of the pesticides prochloraz and methiocarb on human estrogen receptor alpha and beta mRNA levels analyzed by on-line RT-PCR. Toxicol In Vitro. 2004 Aug;18(4):427-33. We have analyzed the effect of the currently used pesticides prochloraz and methiocarb on the estrogen receptor (ER) alpha and beta mRNA levels in parallel with the natural ligand, 17beta- (E2). |
41(0,1,2,6) | Details |
| 11884232 | Andersen HR, Vinggaard AM, Rasmussen TH, Gjermandsen IM, Bonefeld-Jorgensen EC: Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro. Toxicol Appl Pharmacol. 2002 Feb 15;179(1):1-12. Twenty-four pesticides were tested for interactions with the estrogen receptor (ER) and the androgen receptor (AR) in transactivation assays. Pesticides (endosulfan, methiocarb, methomyl, pirimicarb, propamocarb, deltamethrin, fenpropathrin, dimethoate, chlorpyriphos, dichlorvos, tolchlofos-methyl, vinclozolin, iprodion, fenarimol, prochloraz, fosetyl-aluminum, chlorothalonil, daminozid, paclobutrazol, chlormequat chlorid, and ethephon) were selected according to their frequent use in Danish greenhouses. |
1(0,0,0,1) | Details |
| 15788727 | Vinggaard AM, Christiansen S, Laier P, Poulsen ME, Breinholt V, Jarfelt K, Jacobsen H, Dalgaard M, Nellemann C, Hass U: Perinatal exposure to the fungicide prochloraz feminizes the male rat offspring. Toxicol Sci. 2005 Jun;85(2):886-97. Epub 2005 Mar 23. It antagonizes the androgen and the estrogen receptors, agonizes the Ah receptor, and inhibits aromatase activity. The purpose of this study was to investigate reproductive toxic effects after exposure during gestation and lactation to prochloraz alone and a mixture of five pesticides (deltamethrin, methiocarb, prochloraz, simazine, and tribenuron-methyl). |
1(0,0,0,1) | Details |
| 15064155 | Kojima H, Katsura E, Takeuchi S, Niiyama K, Kobayashi K: Screening for and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Environ Health Perspect. 2004 Apr;112(5):524-31. We tested 200 pesticides, including some of their isomers and metabolites, for agonism and antagonism to two human estrogen receptor (hER) subtypes, hERalpha and hERbeta, and a human androgen receptor (hAR) by highly sensitive transactivation assays using Chinese hamster ovary cells. Among them, 29 pesticides had both hERalpha and hERbeta agonistic activities, and the effects of the organochlorine insecticides beta-benzene hexachloride (BHC) and delta-BHC and the insecticide methiocarb were predominantly hERbeta rather than hERalpha agonistic. |
1(0,0,0,1) | Details |