Protein Information

Name Ca v
Synonyms CA V; CA VA; CA5; CA5A; CAV; CAVA; Carbonate dehydratase VA; Carbonic anhydrase V…

Compound Information

Name cismethrin
CAS

Reference List

PubMed Abstract RScore(About this table)
17294162 Clark JM, Symington SB: Pyrethroid action on calcium channels: neurotoxicological implications. Invert Neurosci. 2007 Mar;7(1):3-16. Epub 2007 Feb 9.

Actions of cismethrin versus deltamethrin were compared using two functional attributes of rat brain synaptosomes.
These findings delineate a separate action for deltamethrin and implicate N-type rat brain Ca (v) 2.2 voltage-sensitive calcium channels (VSCC) as target sites that are consistent with the in vivo release of neurotransmitter caused by deltamethrin.
4(0,0,0,4) Details
18383452 Clark JM, Symington SB: Neurotoxic implications of the agonistic action of CS-syndrome pyrethroids on the N-type Ca (v) 2.2 calcium channel. Pest Manag Sci. 2008 Jun;64(6):628-38.

BACKGROUND: Cismethrin (T-syndrome) and deltamethrin (CS-syndrome) pyrethroids have been previously shown to increase membrane depolarization and calcium influx, but only deltamethrin increased Ca (2+)-dependent neurotransmitter release from rat brain synaptosomes.
4(0,0,0,4) Details