| Name | interleukin 1 |
|---|---|
| Synonyms | Catabolin; IL 1; IL 1 beta; IL 1B; IL1 beta; IL1B; IL1F2; Interleukin 1… |
| Name | aldicarb |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2260089 | Dean TN, Kakkanaiah VN, Nagarkatti M, Nagarkatti PS: Immunosuppression by aldicarb of T cell responses to antigen-specific and polyclonal stimuli results from defective IL-1 production by the macrophages. Toxicol Appl Pharmacol. 1990 Dec;106(3):408-17. It was observed that the macrophages from aldicarb-treated mice demonstrated a decreased capacity to stimulate conalbumin-specific T helper cell clone, D10.G4, and when activated produced decreased amounts of IL-1 when compared to control macrophages. |
118(1,2,3,3) | Details |
| 2139433 | Dean TN, Selvan RS, Misra HP, Nagarkatti M, Nagarkatti PS: Aldicarb treatment inhibits the stimulatory activity of macrophages without affecting the T-cell responses in the syngeneic mixed lymphocyte reaction. Int J Immunopharmacol. 1990;12(3):337-48. These data suggested that aldicarb may selectively suppress the stimulatory activity of macrophages by inhibiting IL-1 mediated signal to the T-cells without directly affecting the T-cell functions. |
87(1,1,2,2) | Details |