Protein Information

Name C18
Synonyms B1; D1; BBS 9; BBS9; BBS9 GENE; Bardet Biedl syndrome 9 protein; C18; PTH responsive osteosarcoma B1 protein…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
12541716 Zhu ZJ: [Determination of brucine in seed dressing agents by high performance liquid chromatography]. Se Pu. 2000 Sep;18(5):468-9.


The sample solution was separated on a Spherisorb C18 column (4.6 mm i.d. x 200 mm, 5 microns) with CH3OH-H2O-CTAB (88:12:0.04, m/m) as the mobile phase and detected at 254 nm.
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11596226 Gu ZP, Zhang SM, Wang CL, Lian WY, Xiao PG, Chen JM: [Determation of strychnine and brucine in Strychnos by HPLC] . Yao Xue Xue Bao. 1997 Oct;32(10):791-4.

The analytical column used was ZY110 YNG-C18.
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14513809 Xu XY, Cai BC, Pan Y, Wang TS: [Pharmacokinetics of the alkaloids from the processed seeds of Strychnos nux-vomica in rats]. Yao Xue Xue Bao. 2003 Jun;38(6):458-61.

METHODS: Hypersil BDS C18 column was used and the mobile phase consisted of acetonitrile-water at the flow rate of 0.8 mL.min-1.
RESULTS: The concentration-time data of strychnine, brucine, strychnine N-oxide and brucine N-oxide were all in accordance with an open two-compartment model after i.v. alkaloids.
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