Protein Information

Name alpha 1A adrenoceptor
Synonyms ADRA1A; ADRA1C; ADRA1L1; ALPHA1AAR; Alpha 1A adrenergic receptor; Alpha 1A adrenoceptor; Alpha 1A adrenoreceptor; Alpha 1C adrenergic receptor…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
8816361 del Carmen Garcia M, Enero MA, Celuch SM: Hypotensive and hypertensive effects of catecholamines intrathecally injected in anesthetized rats. J Auton Nerv Syst. 1996 Jun 10;59(1-2):17-26.

The glycine-receptor antagonist strychnine (25 micrograms, i.t.) did not modify the hypotension induced by either noradrenaline (in the presence of prazosin) or adrenaline.
The pressor responses to both catecholamines were antagonized by the alpha 1-adrenoceptor blocker prazosin (0.05-1 microgram, i.t.) and by the selective alpha 1A-adrenoceptor antagonist 5-methyl urapidil (10 and 15 micrograms, i.t.).
2(0,0,0,2) Details