| Name | P2X receptor (protein family or complex) |
|---|---|
| Synonyms | P2X receptor; P2X receptors |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9351519 | Green MA, Halliwell RF: Selective antagonism of the (A) receptor by ciprofloxacin and biphenylacetic acid. Br J Pharmacol. 1997 Oct;122(3):584-90. Responses mediated by 5-HT3, nicotinic and P2X receptors in the vagus nerve and strychnine-sensitive glycine receptors in the optic nerve were little or unaffected by ciprofloxacin (100 microM), BPAA (100 microM) or the combination of these drugs (both at 100 microM). 6. |
32(0,1,1,2) | Details |
| 17537680 | Li DP, Yang Q: Membrane and synaptic properties of nucleus tractus solitarius neurons projecting to the caudal ventrolateral medulla. Auton Neurosci. 2007 Oct 30;136(1-2):69-81. Epub 2007 May 29. The residual spontaneous and evoked EPSCs were abolished by the nicotinic receptor antagonist mecamylamine and the purinergic P2X receptor antagonist iso-PPADS. While the glycine receptor antagonist strychnine had no effect on the firing activity, blockade of (A) receptors with bicuculline significantly increased the firing rate in the majority of labeled NTS neurons. |
1(0,0,0,1) | Details |
| 16822980 | Mulkey DK, Mistry AM, Guyenet PG, Bayliss DA: Purinergic P2 receptors modulate excitability but do not mediate pH sensitivity of RTN respiratory chemoreceptors. J Neurosci. 2006 Jul 5;26(27):7230-3. Using loose-patch current-clamp recordings in brainstem slices from rat pups (postnatal day 7-12), we indeed show purinergic modulation of pH-sensitive RTN neurons: activation of P2X receptors indirectly inhibited RTN firing by increasing inhibitory input, whereas P2Y receptor stimulation caused direct excitation of RTN chemoreceptors. |
1(0,0,0,1) | Details |
| 16360285 | Otsuguro K, Ohta T, Ito S: modulates primary afferent fiber-evoked responses of ventral roots in neonatal rat spinal cord in vitro. Neuroscience. 2006;138(1):281-91. Epub 2005 Dec 19. Unlike Zn (2+), strychnine (5 microM), a glycine receptor antagonist, and (S),9 (R)-(-)-bicuculline methobromide (10 microM), a (A) receptor antagonist, potentiated both fast polysynaptic reflex potential and slow ventral root potential. |
0(0,0,0,0) | Details |