| Name | anticholinesterase |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8890920 | Wang H, Cui WY, Liu CG: Regulatory effects of acutely repeated treatment towards central muscarinic receptors. Life Sci. 1996;59(17):1415-21. In conscious rats, the dose-response curves of muscarinic agonists arecoline and pilocarpine, cholinesterase inhibitors soman and physostigmine rather than GABA receptor antagonist pentylenetetrazol or glycine receptor antagonist strychnine for producing EEG seizures were shifted leftwards by acutely repeated injections of |
31(0,1,1,1) | Details |
| 11181903 | Loomis CW, Khandwala H, Osmond G, Hefferan MP: Coadministration of intrathecal strychnine and bicuculline effects synergistic allodynia in the rat: an isobolographic analysis. J Pharmacol Exp Ther. 2001 Mar;296(3):756-61. The results of this study indicate that 1) and effect cooperative inhibition of low-threshold mechanical input in the spinal cord of the rat; and 2) BIC-allodynia arises from the blockade of (A) receptors and is unrelated to any secondary anticholinesterase activity. |
1(0,0,0,1) | Details |
| 7608751 | Perrins R, Roberts A: Cholinergic contribution to excitation in a spinal locomotor central pattern generator in Xenopus embryos. J Neurophysiol. 1995 Mar;73(3):1013-9. The cholinesterase inhibitor eserine (10 microM) increased the duration of swimming episodes.(ABSTRACT TRUNCATED AT 250 WORDS) After locally blocking inhibitory potentials with 2 microM strychnine and 40 microM bicuculline, the reliability of spike firing and the amplitude of fast, on-cycle, excitatory postsynaptic potentials (EPSPs) underlying the single on-cycle spikes were measured during fictive swimming. 3. |
1(0,0,0,1) | Details |
| 10222829 | Semina II, Tikhonova NA, Baichurina AZ, Tarasova RI, Pavlov VA, Shilovskaia EV, Garaev RS: [Neuroprotective effect of kapakh, representative of new nootropic class non-anticholinesterase organophosphoric compounds]. Vestn Ross Akad Med Nauk. 1999;(3):32-6. The mechanisms of this action, which were due to the membranous stabilizing activity of the drug and its affinity for strychnine-sensitive sites of MMDA receptors (Ki = 8.8.10 (-5) M). |
1(0,0,0,1) | Details |
| 17011596 | Zhao X, Marszalec W, Toth PT, Huang J, Yeh JZ, Narahashi T: In vitro galantamine-memantine co-application: mechanism of beneficial action. Neuropharmacology. 2006 Dec;51(7-8):1181-91. Epub 2006 Sep 29. Galantamine is an anticholinesterase and allosterically potentiates the activity of the nicotinic receptors. |
1(0,0,0,1) | Details |