| Name | Potassium channel (protein family or complex) |
|---|---|
| Synonyms | Potassium channel |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20331561 | Adermark L, Clarke RB, Olsson T, Hansson E, Soderpalm B, Ericson M: Implications for glycine receptors and astrocytes in -induced elevation of levels in the nucleus accumbens. Addict Biol. 2010 Mar 10. ABSTRACT Elevated levels are believed to contribute to the rewarding sensation of (EtOH), and previous research has shown that strychnine-sensitive glycine receptors in the nucleus accumbens (nAc) are involved in regulating release and in mediating the reinforcing effects of EtOH. The EtOH-induced cell swelling was inhibited in cultures treated with the Na (+)/K (+)/2Cl (-) cotransporter blocker (1 mM), Na (+)/K (+)-ATPase inhibitor ouabain (0.1 mM), potassium channel inhibitor BaCl (2) (50 microM) and in cultures containing low extracellular concentration (3 mM). |
1(0,0,0,1) | Details |
| 8667245 | Sorenson EM, Gallagher JP: The membrane hyperpolarization of rat dorsolateral septal nucleus neurons is mediated by a novel nicotinic receptor. J Pharmacol Exp Ther. 1996 Jun;277(3):1733-43. These results indicate that the nicotinic response in DLSN neurons may be mediated by a metabotropic nicotinic receptor coupled to a -dependent potassium channel through the activation of a G-protein and release of intracellular stores. Intracellular recording from DSLN neurons in a brain slice preparation was used to determine whether chlorisondamine, trimethaphan, cytisine or strychnine inhibited the membrane hyperpolarization in response to application of the nicotinic agonist 1,1-dimethyl-4-phenylpiperazinium |
1(0,0,0,1) | Details |
| 7500153 | Lev-Tov A, O'Donovan MJ: imaging of motoneuron activity in the en-bloc spinal cord preparation of the neonatal rat. J Neurophysiol. 1995 Sep;74(3):1324-34. Substantial changes in fluorescence of green-labeled motoneurons were also observed during motoneuron bursting induced by bath application of the glycine receptor antagonist strychnine or the potassium channel blocker 4-aminopyridine (4-AP). 7. |
31(0,1,1,1) | Details |
| 8234367 | Sladeczek F, Momiyama A, Takahashi T: Presynaptic inhibitory action of a metabotropic glutamate receptor agonist on excitatory transmission in visual cortical neurons. Proc Biol Sci. 1993 Sep 22;253(1338):297-303. This effect on the evoked EPSCS was blocked by a potassium channel blocker, 4-aminopyridine (4-AP) in a dose-dependent manner. |
1(0,0,0,1) | Details |
| 16888071 | Dombkowski RA, Doellman MM, Head SK, Olson KR: mediates hypoxia-induced relaxation of trout urinary bladder smooth muscle. J Exp Biol. 2006 Aug;209(Pt 16):3234-40. Inhibitors of neuronal mechanisms, tetrodotoxin, strychnine and N-vanillylnonanamide were likewise ineffective. |
0(0,0,0,0) | Details |
| 15056699 | Nakayama H, Oda Y: Common sensory inputs and differential excitability of segmentally homologous reticulospinal neurons in the hindbrain. J Neurosci. 2004 Mar 31;24(13):3199-209. This atypical property of the M-cell was mediated by dendrotoxin-I (DTX-I)-sensitive voltage-gated potassium channels together with recurrent inhibition, because combined application of DTX-I, strychnine, and bicuculline led to continuous repetitive firing in M-cells. |
0(0,0,0,0) | Details |