Protein Information

Name cyclin A
Synonyms CCN 1; CCN1; CCNA; CCNA 2; CCNA2; Cyclin A; Cyclin A2; Cyclin As…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
18446845 Lee SM, Kwon JI, Choi YH, Eom HS, Chi GY: Induction of G2/M arrest and apoptosis by water extract of Strychni Semen in human gastric carcinoma AGS cells. Phytother Res. 2008 Jun;22(6):752-8.


ESS-mediated G2/M arrest was found to be associated with up-regulation of cyclin A, Cdc2, tumor suppressor p53 and cyclin dependent kinase (Cdk) inhibitor p21 (WAF1/CIP1), whereas the expressions of other G2/M regulatory proteins, including cyclin B1 and Cdk2, were down-regulated compared with the control.
1(0,0,0,1) Details