Protein Information

Name GTPase
Synonyms RAC3; RAC3; Ras related C3 botulinum substrate 3; Ras related C3 botulinum toxin substrate 3; p21 Rac3; Ras related C3 botulinum substrate 3s; Ras related C3 botulinum toxin substrate 3s; p21 Rac3s…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
10101037 Birdsall NJ, Farries T, Gharagozloo P, Kobayashi S, Lazareno S, Sugimoto M: Subtype-selective positive cooperative interactions between brucine analogs and acetylcholine at muscarinic receptors: functional studies. Mol Pharmacol. 1999 Apr;55(4):778-86.


The enhancing actions of brucine and brucine N-oxide on acetylcholine (ACh) potency at M1 and M4 receptors respectively have been confirmed in guanosine-5'-O-(3-[35S] thio) triphosphate, GTPase, cAMP, and intracellular Ca2+ mobilization assays of function.
1(0,0,0,1) Details