Protein Information

Name MAPK (protein family or complex)
Synonyms MAPK; mitogen activated protein kinase; mitogen activated protein kinases

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
17553349 Chen GX, Tong J, Liu QP, Shen XY, Zhao SZ, Zeng YY, Chen JF: [Paharmacological mechanisms of cellular immunity of overall alkali of tongbiling for the treatment of joint destruction]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2007 Jun;23(6):527-30.

CONCLUSION: Overall alkali of TBL could relieve joint inflammation and destruction of CIA rats by blocking the MAPK cell signalling pathway to inhibit the activation and proliferation of T cells.
AIM: To investigate the effect of the overall alkali of Traditional Chinese Medicine tongbiling (TBL) which comprises brucine and strychnine alkaloids on collagen induced-arthritis (CIA) and study its paharmacological mechanisms of cellular immunity.
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