Protein Information

Name CD50
Synonyms CD50; CD50 antigen; CDW50; ICAM 3; ICAM R; ICAM3; Intercellular adhesion molecule 3; Intercellular adhesion molecule 3 precursor…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
12575379 Wang LF, Zhao ML, Liu Y: [Experimental pharmacodynamic study on the anti-convulsion effect of shenpu decoction]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2001 Nov;21(11):837-9.

RESULTS: In cardiazol convulsion model, the CD50 detected in group A-E were 63.3 +/- 3.4 mg/kg, 116.2 +/- 3.4 mg/kg, 105.6 +/- 3.7 mg/kg, 74.0 +/- 3.7 mg/kg and 197.2 +/- 3.3 mg/kg respectively, while they were 0.71 +/- 0.04 mg/kg, 1.21 +/- 0.04 mg/kg, 1.19 +/- 0.04 mg/kg, 0.94 +/- 0.04 mg/kg and 1.16 +/- 0.04 mg/kg respectively in the strychnine convulsion model, and 67.1 +/- 2.6 V, > 140 V, 109.4 +/- 3.5 V, 84.4 +/- 3.1 V and 128.4 +/- 3.9 V in the maximal electrical shock model respectively.
7(0,0,1,2) Details