Protein Information

Name integrator (protein family or complex)
Synonyms Integrator; Integrator complex

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
10755164 Arnold DB, Robinson DA, Leigh RJ: Nystagmus induced by pharmacological inactivation of the brainstem ocular motor integrator in monkey. Vision Res. 1999;39(25):4286-95.

Agents with agonist or antagonist actions at gamma-aminobutyric acid (GABA), glutamate, and kainate receptors all caused gaze-evoked nystagmus with centripetal eye drifts; glycine and strychnine had no effect.
4(0,0,0,4) Details
18826652 Vandam RJ, Shields EJ, Kelty JD: Rhythm generation by the pre-Botzinger complex in medullary slice and island preparations: effects of adenosine A (1) receptor activation. BMC Neurosci. 2008 Oct 1;9:95.


RESULTS: Converting medullary slices to islands by cutting away much of the medullary tissue adjacent to the preBotC decreased the amplitude of action potential bursts generated by a population of neurons within the preBotC (recorded with an extracellular electrode, and integrated using a hardware integrator), without noticeably affecting burst frequency.
1(0,0,0,1) Details