Protein Information

Name alpha 1B adrenoceptor
Synonyms ADRA 1; ADRA1; ADRA1B; ALPHA1BAR; Alpha 1 adrenergic receptor; Alpha 1B adrenergic receptor; Alpha 1B adrenoceptor; Alpha 1B adrenoreceptor…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
8816361 del Carmen Garcia M, Enero MA, Celuch SM: Hypotensive and hypertensive effects of catecholamines intrathecally injected in anesthetized rats. J Auton Nerv Syst. 1996 Jun 10;59(1-2):17-26.

The glycine-receptor antagonist strychnine (25 micrograms, i.t.) did not modify the hypotension induced by either noradrenaline (in the presence of prazosin) or adrenaline.
The pressor responses of high doses of i.t. injected catecholamines could be mediated by the activation of spinal alpha 1A-adrenoceptors, although the participation of alpha 1B-adrenoceptors cannot be rule out entirely.
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11929913 Pan YZ, Li DP, Pan HL: Inhibition of glutamatergic synaptic input to spinal lamina II (o) neurons by presynaptic alpha (2)-adrenergic receptors. J Neurophysiol. 2002 Apr;87(4):1938-47.


The miniature excitatory postsynaptic currents (mEPSCs) were recorded in the presence of tetrodotoxin, bicuculline, and strychnine.
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