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Blisard KS, Fagin K, Falivena P, Privitera MD, Olejniczak P, Harrington DA, Taylor KL, Scremin OU: Experimental seizures in the frog (Rana pipiens). Epilepsy Res. 1994 Jan;17(1):13-22.
Systemic kainic acid (5-20 mg/kg) caused limbic-like seizures, with staring, catatonia, fasciculations, and severe motor seizures, which were almost always lethal.
Strychnine (1-5 mg/kg) caused reversible seizures characterized by tonic extensions of the extremities, that seemed to originate in the spinal cord. |
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