Protein Information

Name NK 1
Synonyms B3GAT1; CD57; CD57 antigen; GLCATP; Galactosylgalactosylxylosylprotein 3 beta glucuronosyltransferase 1; GlcAT I; GlcAT P; GlcUAT P…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
9080374 Russo RE, Nagy F, Hounsgaard J: Modulation of plateau properties in dorsal horn neurones in a slice preparation of the turtle spinal cord. J Physiol. 1997 Mar 1;499 ( Pt 2):459-74.

The facilitation of plateau properties produced by dorsal root stimulation was also reduced by antagonists of metabotropic glutamate receptors and NK-1 tachykinin receptors. 9.
The tetanic stimulus facilitated wind-up and after-discharges even when fast synaptic transmission was blocked by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX, 10-20 microM), (+/-)-2-amino-5-phosphonopentanoic acid (AP5, 100 microM), bicuculline (10-20 microM) and strychnine (5-20 microM). 2.
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12435818 Lazareno S, Popham A, Birdsall NJ: Analogs of WIN 62,577 define a second allosteric site on muscarinic receptors. Mol Pharmacol. 2002 Dec;62(6):1492-505.


The interaction between PG987 and other allosteric agents on [(3) H] NMS dissociation from M (3) receptors indicate that PG987 binds reversibly to a site distinct from that to which gallamine and strychnine bind: in contrast, PG987 seems to bind to the same site on M (3) receptors as KT5720, staurosporine, and WIN 51,708.
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