Protein Information

Name taurine transporter
Synonyms SLC6A6; Sodium and chloride dependent taurine transporter; Sodium and chloride dependent taurine transporter; TAUT; Taurine transporter; Sodium and chloride dependent taurine transporters; Sodium and chloride dependent taurine transporters; Taurine transporters

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
12405966 Chepkova AN, Doreulee N, Yanovsky Y, Mukhopadhyay D, Haas HL, Sergeeva OA: Long-lasting enhancement of corticostriatal neurotransmission by taurine. . Eur J Neurosci. 2002 Oct;16(8):1523-30.

Activation of GlyRs and the specific taurine transporter by taurine evoke a long-lasting enhancement of corticostriatal transmission.
The LLETAU was not prevented by N-methyl-d-aspartate (NMDA)- or by GABAA receptor-antagonists, but was sensitive to the GlyR-antagonist strychnine and blocked by the competitive taurine uptake inhibitor guanidinoethylsulphonate (GES, 1 mm).
1(0,0,0,1) Details
12154171 Mangin JM, Guyon A, Eugene D, Paupardin-Tritsch D, Legendre P: Functional glycine receptor maturation in the absence of glycinergic input in dopaminergic neurones of the rat substantia nigra. J Physiol. 2002 Aug 1;542(Pt 3):685-97.

Blockade of taurine transporters and applications of high K (+) and hyposmotic solutions were also unable to induce any strychnine-sensitive current.
31(0,1,1,1) Details