Protein Information

Name neural cell adhesion molecule
Synonyms CALL; CHL 1; CHL1; Cell adhesion molecule L1 like; Close homolog of L1; L1 Cell adhesion molecule 2; L1CAM2; Neural cell adhesion molecule…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
15094457 Nguyen L, Malgrange B, Breuskin I, Lallemend F, Hans G, Moonen G, Belachew S, Rigo JM: Striatal PSA-NCAM (+) precursor cells from the newborn rat express functional glycine receptors. Neuroreport. 2004 Mar 22;15(4):583-7.

Immunocytochemical analysis showed that ionotropic glycine receptors are expressed in neurogenic progenitors purified from the newborn rat striatum and expressing the polysialylated form of the neural cell adhesion molecule, both in vitro and in situ.
To ascertain whether glycine receptors were functional in vitro, whole-cell patch-clamp recordings demonstrated that glycine triggers inward strychnine-sensitive currents in the majority of these cells.
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