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Nguyen L, Malgrange B, Breuskin I, Lallemend F, Hans G, Moonen G, Belachew S, Rigo JM: Striatal PSA-NCAM (+) precursor cells from the newborn rat express functional glycine receptors. Neuroreport. 2004 Mar 22;15(4):583-7.
Immunocytochemical analysis showed that ionotropic glycine receptors are expressed in neurogenic progenitors purified from the newborn rat striatum and expressing the polysialylated form of the neural cell adhesion molecule, both in vitro and in situ. To ascertain whether glycine receptors were functional in vitro, whole-cell patch-clamp recordings demonstrated that glycine triggers inward strychnine-sensitive currents in the majority of these cells. |
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