| Name | somatostatin |
|---|---|
| Synonyms | Growth hormone release inhibiting factor; SMST; SST; Somatostatin; Somatostatin precursor; Somatostatins; Somatostatin precursors |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7913402 | Puebla L, Arilla E: Somatostatin receptor-GTP binding regulatory protein-adenylyl cyclase system in hippocampal membranes of strychnine-treated rats. Brain Res. 1994 Apr 25;644(1):59-66. |
143(1,3,3,3) | Details |
| 19782664 | Yin H, Lee KE, Park SA, Bhattarai JP, Suh BJ, Jeon JG, Kim BG, Park SJ, Han SK: Inhibitory effects of somatostatin on the substantia gelatinosa neurons of trigeminal subnucleus caudalis via somatostatin type 2 receptors in juvenile mice. Brain Res. 2009 Dec 22;1304:49-56. Epub 2009 Sep 24. The SST-induced hyperpolarizing response was maintained in the presence of TTX (Na (+) channel blocker), AP-5 (NMDA receptor antagonist), CNQX (non- glutamate receptor antagonist), picrotoxin (A) receptor antagonist) and strychnine (glycine receptor antagonist), respectively, suggesting that SST has direct effects on the postsynaptic SG neurons. |
2(0,0,0,2) | Details |
| 8714523 | Puebla L, Arilla E: increases the number of somatostatin receptors and somatostatin-mediated inhibition of the adenylate cyclase system in the rat hippocampus. J Neurosci Res. 1996 Feb 1;43(3):346-54. This effect seems to be mediated by inhibitory strychnine-sensitive glycine receptors since pretreatment with the antagonist strychnine (80 micrograms/100 g body weight, intravenously) abolished this response. |
2(0,0,0,2) | Details |
| 9758163 | Paudice P, Gemignani A, Raiteri M: Evidence for functional native NMDA receptors activated by or alone in the absence of glutamatergic coagonist. Eur J Neurosci. 1998 Sep;10(9):2934-44. In this study we have examined the effects of (NMDA) receptor activation on the release of cholecystokinin and somatostatin from rat neocortical nerve endings. This effect of was strychnine-insensitive and could be mimicked by a stereoselective agonist at the NMDA receptor site. |
1(0,0,0,1) | Details |