Protein Information

Name synaptophysin
Synonyms Major synaptic vesicle protein p38; p38; Syp; Major syp38naptic vesicle protein; Synaptophysin; Major syp38naptic vesicle proteins; Synaptophysins

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
11738262 Tapia JC, Mentis GZ, Navarrete R, Nualart F, Figueroa E, Sanchez A, Aguayo LG: Early expression of glycine and GABA (A) receptors in developing spinal cord neurons. Neuroscience. 2001;108(3):493-506.

Further evidence for functional synaptic activity was provided by the detection of co-localization of gephyrin and synaptophysin at 5 DIV using confocal microscopy.
The use of various receptor antagonists (strychnine, bicuculline, DL-2-amino-5-phosphonovalerate [APV], 6-cyano-7-nitroquinoxaline-2,3-dione [CNQX]) revealed that this activity was predominantly glycinergic, and to a smaller extent, GABAergic.
1(0,0,0,1) Details