Protein Information

Name monoamine oxidase
Synonyms Adrenalin oxidase; Amine oxidase; Amine oxidase [flavin containing] B; MAO B; MAOB; Monoamine oxidase; Monoamine oxidase B; Monoamine oxidase type B…

Compound Information

Name amitraz
CAS

Reference List

PubMed Abstract RScore(About this table)
15822764 Gursoy S, Kunt N, Kaygusuz K, Kafali H: Intravenous amitraz poisoning. Clin Toxicol. 2005;43(2):113-6.

Amitraz inhibits monoamine oxidase and prostaglandin synthesis and is an alpha-2 adrenergic agonist.
81(1,1,1,1) Details
6642515 Bonsall JL, Turnbull GJ: Extrapolation from safety data to management of poisoning with reference to amitraz (a formamidine pesticide) and xylene. Hum Toxicol. 1983 Oct;2(4):587-92.

Amitraz has pharmacological activity, including monoamine oxidase inhibition, alpha-adrenergic agonist activity and it inhibits prostaglandin synthesis.
31(0,1,1,1) Details
2925011 Moser VC, MacPhail RC: Investigations of amitraz neurotoxicity in rats. Fundam Appl Toxicol. 1989 Jan;12(1):12-22.

Effects on motor activity and inhibition of monoamine oxidase..
2(0,0,0,2) Details
17448604 Jonsson NN, Hope M: Progress in the epidemiology and diagnosis of amitraz resistance in the cattle tick Boophilus microplus. Vet Parasitol. 2007 May 31;146(3-4):193-8. Epub 2007 Apr 19.

Two possibilities have been proposed: octopamine receptor and monoamine oxidase.
1(0,0,0,1) Details