| Name | transferase |
|---|---|
| Synonyms | 4' phosphopantetheinyl transferase; 4' phosphopantetheinyl transferase; AASD PPT; AASDHPPT; AASDPPT; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Aminoadipate semialdehyde dehydrogenase phosphopantetheinyl transferase; CGI 80… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18989868 | Nogueira CW, Borges LP, Souza AC: Oral administration of diphenyl diselenide potentiates hepatotoxicity induced by carbon tetrachloride in rats. J Appl Toxicol. 2009 Mar;29(2):156-64. Pre-treatment with a single dose of (PhSe) 2 prevented the effect of strychnine, a substrate for CYPs, abolishing lethality in mice. The liver and kidney were utilized for determination of histopathology, biochemical (ALT) and alanine (AST) aminotransferases, alkaline phosphatase (ALP), total bilirrubin (TB) and gamaglutamyl transferase (GGT)] and toxicological parameters [thiobarbituric reactive species (TBARS) levels, catalase activity, nonprotein thiols (NPSH) and aminolevulinate dehydratase (-ALA-D) activity]. |
1(0,0,0,1) | Details |
| 10651109 | Mercuri NB, Federici M, Bernardi G: Inhibition of catechol-O-methyltransferase (COMT) in the brain does not affect the action of and an in vitro electrophysiological evidence from rat mesencephalic neurons. J Neural Transm. 1999;106(11-12):1135-40. In order to study whether the membrane hyperpolarization and firing inhibition caused by and on rat midbrain cells are affected by the inhibition of brain -O-methyl-transferase (COMT), intracellular electrophysiological recordings were made from these neurons maintained in vitro. |
1(0,0,0,1) | Details |
| 10960447 | Zhang Y, Ikejima K, Honda H, Kitamura T, Takei Y, Sato N: prevents apoptosis of rat sinusoidal endothelial cells caused by deprivation of vascular endothelial growth factor. Hepatology. 2000 Sep;32(3):542-6. Furthermore, strychnine (1 micromol/L), a glycine receptor antagonist, inhibited this effect of suggesting the possible involvement of the glycine receptor/chloride channel in the mechanism. Apoptosis was detected by terminal deoxynucleotidyl transferase (TdT)-mediated d- - nick end labeling (TUNEL) staining in these conditions. |
1(0,0,0,1) | Details |