Protein Information

Name metabotropic glutamate receptor 4
Synonyms GPRC1D; GRM 4; GRM4; MGLUR4; Metabotropic glutamate receptor 4; Metabotropic glutamate receptor 4 precursor; mGLUR 4; mGlu4…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
10934271 Snead OC 3rd, Banerjee PK, Burnham M, Hampson D: Modulation of absence seizures by the GABA (A) receptor: a critical rolefor metabotropic glutamate receptor 4 (mGluR4). J Neurosci. 2000 Aug 15;20(16):6218-24.

No differences were observed between mGluR4 (-/-) and mGluR4 (+/+) mice in threshold to clonic or tonic seizures induced by higher doses of GABA (A) R antagonists, strychnine, or electroshock, indicating that seizure resistance in the mGluR4 (-/-) mice was restricted solely to absence seizures.
6(0,0,0,6) Details