Protein Information

Name purinergic receptor
Synonyms ATP receptor; Purinergic receptor; HP2U; P2RU1; P2RY2; P2U; P2U Purinoceptor 1; P2U nucleotide receptor…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
11790816 Grudt TJ, van den Pol AN, Perl ER: Hypocretin-2 (orexin-B) modulation of superficial dorsal horn activity in rat. J Physiol. 2002 Jan 15;538(Pt 2):517-25.

The inward current and noise were unaffected by TTX but were blocked by the P (2X) purinergic receptor antagonist suramin (300-500 microM).
The sIPSC increase was blocked by strychnine (1 microM) and by TTX (1 microM), suggesting that the increased sIPSC frequency was glycine and action potential dependent.
1(0,0,0,1) Details