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Lin HH, Wu SY, Lai CC, Dun NJ: GABA- and glycine-mediated inhibitory postsynaptic potentials in neonatal rat rostral ventrolateral medulla neurons in vitro. Neuroscience. 1998 Jan;82(2):429-42.
Medullary neurons were characterized as: (i) spinally projecting by the appearance of an antidromic spike following electrical stimulation of the spinal tract between T2 and T3 segments, and (ii) adrenergic by the detection of phenylethanolamine-N-methyltransferase immunoreactivity in Lucifer Yellow-filled neurons.
Inhibitory synaptic potentials were reversibly eliminated by the GABA (A) receptor antagonist bicuculline (10-20 microM) in six of nine neurons, by the glycine receptor antagonist strychnine (0.1-1 microM) in two and by a combination of bicuculline and strychnine in one neuron. |
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