| Name | 5 HT1A |
|---|---|
| Synonyms | 5 HT 1A; serotonin receptor; 5 HT1A; 5 hydroxytryptamine (serotonin) receptor 1A; 5 hydroxytryptamine 1A receptor; 5HT1A; ADRB2RL1; ADRBRL 1… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8539344 | Molewijk HE, van der Poel AM, Olivier B: The ambivalent behaviour "stretched approach posture" in the rat as a paradigm to characterize anxiolytic drugs. Psychopharmacology. 1995 Sep;121(1):81-90. Finally, the 5-HT2C receptor antagonist ritanserine, the CCKA receptor antagonist devazepide, the CCKB receptor antagonist L-365.260 and the strychnine-insensitive site antagonist 7-Cl- were without effect on the behaviours in this paradigm using single doses. The benzodiazepine receptor agonists chlordiazepoxide, diazepam and alprazolam, the 5-HT1A receptor agonists flesinoxan and ipsapirone and the uptake inhibitor clomipramine selectively (no effect on crossings) reduced SAP. |
2(0,0,0,2) | Details |
| 9547397 | Pierrefiche O, Schwarzacher SW, Bischoff AM, Richter DW: Blockade of synaptic inhibition within the pre-Botzinger complex in the cat suppresses respiratory rhythm generation in vivo. J Physiol. 1998 May 15;509 ( Pt 1):245-54. Potentiation of synaptic inhibition by the serotonin 1A receptor agonist 8-hydroxydipropylaminotetralin (8-OH-DPAT; 50 microM) restored rhythmic activity only when given shortly after strychnine and bicuculline applications. |
31(0,1,1,1) | Details |
| 12204190 | Jung ME, Lal H, Gatch MB: The discriminative stimulus effects of pentylenetetrazol as a model of anxiety: recent developments. Neurosci Biobehav Rev. 2002 Jun;26(4):429-39. Several classes of compounds can modulate the PTZ discriminative stimulus including 5-HT (1A), 5-HT (3), and L-type calcium channel ligands. |
1(0,0,0,1) | Details |