| Name | alanine aminotransferase |
|---|---|
| Synonyms | AAT1; AAT1; GPT; ALT 1; ALT1; Alanine aminotransferase; Alanine aminotransferase 1; GPT 1… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18989868 | Nogueira CW, Borges LP, Souza AC: Oral administration of diphenyl diselenide potentiates hepatotoxicity induced by carbon tetrachloride in rats. J Appl Toxicol. 2009 Mar;29(2):156-64. Pre-treatment with a single dose of (PhSe) 2 prevented the effect of strychnine, a substrate for CYPs, abolishing lethality in mice. The liver and kidney were utilized for determination of histopathology, biochemical (ALT) and alanine (AST) aminotransferases, alkaline phosphatase (ALP), total bilirrubin (TB) and gamaglutamyl transferase (GGT)] and toxicological parameters [thiobarbituric reactive species (TBARS) levels, catalase activity, nonprotein thiols (NPSH) and aminolevulinate dehydratase (-ALA-D) activity]. |
1(0,0,0,1) | Details |
| 15730916 | Zhang SJ, Shi JH, Tang Z, Wu Y, Chen S: Protective effects of pretreatment on brain-death donor liver. . Hepatobiliary Pancreat Dis Int. 2005 Feb;4(1):37-40. METHODS: Fourty-two male Wistar rats were randomly divided into brain-death donor (BDD) group (B), pretreatment group with BDD (G), and strychnine pretreatment group with BDD (S). Before cold rinsing at 2 and 6 hours after portal vein (PV) reperfusion, blood samples were taken from infrahepatic vena cava (IHVC) to determine the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), tumor necrosis factor alpha (TNF-alpha) and (HA). |
1(0,0,0,1) | Details |