| Name | calcium channel (protein family or complex) |
|---|---|
| Synonyms | calcium channel |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9409718 | Straub H, Kohling R, Speckmann EJ: Strychnine-induced epileptiform activity in hippocampal and neocortical slice preparations: suppression by the organic antagonists and flunarizine. Brain Res. 1997 Oct 31;773(1-2):173-80. To test for this, the antiepileptic effect of the specific L-type calcium channel blocker, in hippocampal and neocortical slices was investigated. |
3(0,0,0,3) | Details |
| 12204190 | Jung ME, Lal H, Gatch MB: The discriminative stimulus effects of pentylenetetrazol as a model of anxiety: recent developments. Neurosci Biobehav Rev. 2002 Jun;26(4):429-39. Several classes of compounds can modulate the PTZ discriminative stimulus including 5-HT (1A), 5-HT (3), and L-type calcium channel ligands. |
1(0,0,0,1) | Details |
| 10627581 | Iwasaki S, Momiyama A, Uchitel OD, Takahashi T: Developmental changes in calcium channel types mediating central synaptic transmission. J Neurosci. 2000 Jan 1;20(1):59-65. |
1(0,0,0,1) | Details |
| 10564356 | Jiang Z, Rempel J, Li J, Sawchuk MA, Carlin KP, Brownstone RM: Development of L-type channels and a nifedipine-sensitive motor activity in the postnatal mouse spinal cord. Eur J Neurosci. 1999 Oct;11(10):3481-7. The electrophysiological data were obtained during rhythmic bursting produced by application of and strychnine to the isolated spinal cord at various postnatal ages. These results demonstrate that in the spinal cord, the L-type calcium channel profile develops both physiologically and anatomically in the early postnatal period. |
1(0,0,0,1) | Details |
| 9112643 | Nowak G: antagonists in the olfactory bulbectomy animal model of depression: effect on the cortical NMDA receptor complex. Pol J Pharmacol. 1996 Mar-Apr;48(2):137-43. Voltage-dependent calcium channel (VDCC) antagonists are active in the forced swim test and in learned helplessness behavioral paradigms, suggesting their antidepressant efficacy. We report that chronic administration of (20 mg/kg) and (10 mg/kg) did not reduced OB-induced hyperactivity, although these drugs reduced the potency of to inhibit [3H] 5,7-dichlorokynurenic acid (DCKA) binding to strychnine-insensitive sites of the NMDA receptor complex. |
1(0,0,0,1) | Details |
| 18497354 | Petit-Jacques J, Bloomfield SA: Synaptic regulation of the light-dependent oscillatory currents in starburst amacrine cells of the mouse retina. J Neurophysiol. 2008 Aug;100(2):993-1006. Epub 2008 May 21. Strychnine, the blocker of glycine receptors did not affect the initial peak but strongly decreased the oscillations frequency. Light responses were inhibited by the calcium channel blockers cadmium ions and nifedipine, suggesting that the release of was dependent. |
1(0,0,0,1) | Details |
| 10816317 | Lieske SP, Thoby-Brisson M, Telgkamp P, Ramirez JM: Reconfiguration of the neural network controlling multiple breathing patterns: eupnea, sighs and gasps [see comment]. Nat Neurosci. 2000 Jun;3(6):600-7. Sighs were triggered by eupneic bursts under control conditions, but not in the presence of strychnine (1 microM). Although all neurons received synaptic inputs during both activities, the calcium channel blocker cadmium (4 microM) selectively abolished sighs. |
1(0,0,0,1) | Details |
| 9786501 | Platt B, Bate JR, von Linstow Roloff E, Withington DJ: induces a novel form of long-term potentiation in the superficial layers of the superior colliculus. Br J Pharmacol. 1998 Sep;125(2):293-300. LTPgly could only be masked but not prevented by strychnine (100 microM) and remained undisturbed in the presence of picrotoxin (100 microM). 5. As indicated by the inhibition of LTPgly of the fEPSP slope by the L-type calcium channel blocker nifedipine (20 microM), voltage-dependent channels are the source for Ca2+ elevation as the intracellular trigger. 7. |
1(0,0,0,1) | Details |
| 8182432 | Sillar KT, Simmers AJ: Presynaptic inhibition of primary afferent transmitter release by at a mechanosensory synapse in the vertebrate spinal cord. J Neurosci. 1994 May;14(5 Pt 1):2636-47. The inhibitory potentials are abolished by strychnine and curare, respectively. |
0(0,0,0,0) | Details |
| 9747898 | Peters SM, de Jong MD, Bindels RJ, van Os CH, Wetzels JF: Effects of renal cytoprotective agents on erythrocyte membrane stability. Life Sci. 1998;63(11):975-83. Freshly isolated rabbit erythrocytes were subjected to a hypotonic shock, and the protective effects of various calcium channel blockers, phospholipase inhibitors, free fatty acids, the NO-synthase inhibitor L-NAME, the amino acid and its receptor-analogue strychnine, and two chloride channel blockers were examined. |
0(0,0,0,0) | Details |