| Name | cone photoreceptors (protein family or complex) |
|---|---|
| Synonyms | Cone photoreceptor; Cone photoreceptors |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16396929 | Balse E, Tessier LH, Forster V, Roux MJ, Sahel JA, Picaud S: Glycine receptors in a population of adult mammalian cones. J Physiol. 2006 Mar 1;571(Pt 2):391-401. Epub 2006 Jan 5. To determine if cones receive such a signal, was applied on cultured porcine cone photoreceptors recorded with the patch clamp technique. These -elicited currents were sensitive to strychnine but not to picrotoxin consistent with the expression of alpha-beta-heteromeric glycine receptors. |
5(0,0,0,5) | Details |
| 16930437 | Perez-Leon JA, Warren EJ, Allen CN, Robinson DW, Lane Brown R: Synaptic inputs to retinal ganglion cells that set the circadian clock. Eur J Neurosci. 2006 Aug;24(4):1117-23. Although strychnine (Strych)-sensitive mPSCs were evident on many non-ipRGCs, indicating the presence of glycinergic inputs, we saw no evidence of Strych-sensitive events in ipRGCs. This and other non-visual responses to light are lost only when the melanopsin deficiency is coupled with mutations that disable classical rod and cone photoreceptors, suggesting that melanopsin-containing RGCs also receive rod- and cone-driven synaptic inputs. |
2(0,0,0,2) | Details |
| 19571128 | Crook JD, Davenport CM, Peterson BB, Packer OS, Detwiler PB, Dacey DM: Parallel ON and OFF cone bipolar inputs establish spatially coextensive receptive field structure of blue-yellow ganglion cells in primate retina. J Neurosci. 2009 Jul 1;29(26):8372-87. In the primate retina the small bistratified, "blue-yellow" color-opponent ganglion cell receives parallel ON-depolarizing and OFF-hyperpolarizing inputs from short (S)-wavelength sensitive and combined long (L)- and middle (M)-wavelength sensitive cone photoreceptors, respectively. The GABAa/c receptor antagonist picrotoxin and the glycine receptor antagonist strychnine did not affect chromatic balance or the basic coextensive receptive field structure, suggesting that the LM-OFF field is not generated by an inner retinal inhibitory pathway. |
1(0,0,0,1) | Details |
| 12242098 | Luo DG, Li GL, Yang XL: Zn (2+) modulates light responses of color-opponent bipolar and amacrine cells in the carp retina. Brain Res Bull. 2002 Sep 15;58(5):461-8. The Zn (2+) effects persisted in the presence of picrotoxin and strychnine, suggesting that modulation by Zn (2+) of and glycine receptors was unlikely involved. Using whole-cell recording techniques, it was found Ca (2+) currents in cone terminals were dose-dependently suppressed by Zn (2+), suggesting that Zn (2+) may reduce release from cone photoreceptors. |
1(0,0,0,1) | Details |
| 15601738 | Protti DA, Flores-Herr N, Li W, Massey SC, Wassle H: Light signaling in scotopic conditions in the rabbit, mouse and rat retina: a physiological and anatomical study. J Neurophysiol. 2005 Jun;93(6):3479-88. Epub 2004 Dec 15. Consistent with this result, strychnine, a glycine receptor antagonist, was unable to abolish these off responses. Two alternative pathways have recently been postulated for the signal transfer in scotopic conditions: 1) electrical coupling between rods and cones, and 2) a circuit independent of cone photoreceptors, implying direct contacts between rods and off CB cells. |
1(0,0,0,1) | Details |