| Name | mGluR6 |
|---|---|
| Synonyms | CSNB1B; GPRC1F; GRM 6; GRM6; MGLUR 6; MGLUR6; Metabotropic glutamate receptor 6; Metabotropic glutamate receptor 6 precursor… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15229213 | Wong KY, Adolph AR, Dowling JE: Retinal bipolar cell input mechanisms in giant danio. J Neurophysiol. 2005 Jan;93(1):84-93. Epub 2004 Jun 30. In conclusion: 1) cone signals onto on bipolar cells involve mainly EAATs but also mGluRs (presumably mGluR6) to a lesser extent; 2) rods signal onto on bipolars by mainly mGluR6; 3) off bipolar cells receive signals from both photoreceptor types by AMPA/kainate receptors. Picrotoxin, strychnine, and tetrodotoxin were used to isolate the effects of the analogs to the photoreceptor-bipolar cell synapse. |
1(0,0,0,1) | Details |
| 19571128 | Crook JD, Davenport CM, Peterson BB, Packer OS, Detwiler PB, Dacey DM: Parallel ON and OFF cone bipolar inputs establish spatially coextensive receptive field structure of blue-yellow ganglion cells in primate retina. J Neurosci. 2009 Jul 1;29(26):8372-87. ON pathway block with l-AP-4, the mGluR6 receptor agonist, abolished the S-ON response but spared the LM-OFF response. The GABAa/c receptor antagonist picrotoxin and the glycine receptor antagonist strychnine did not affect chromatic balance or the basic coextensive receptive field structure, suggesting that the LM-OFF field is not generated by an inner retinal inhibitory pathway. |
1(0,0,0,1) | Details |